碧云天生物技术-ER-Tracker Red (内质网红色荧光探针)(C1041S)

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试剂> 细胞相关> 细胞组织染色> 荧光染色

ER-Tracker Red (内质网红色荧光探针)

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产品编号: C1041S

产品包装:20μl

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产品编号	产品名称	产品包装	产品价格
C1041S	ER-Tracker Red (内质网红色荧光探针)	20μl	1303.00元
C1041M	ER-Tracker Red (内质网红色荧光探针)	100μl	3598.00元
C1041L	ER-Tracker Red (内质网红色荧光探针)	500μl	9998.00元

ER-Tracker Red是一种具有细胞膜通透性的内质网(endoplasmic reticulum, ER)红色荧光探针，对内质网有高度选择性，可以用于活细胞内质网特异性荧光染色。
ER-Tracker Red为采用Molecular Probes公司的BODIPY TR进行了荧光标记的glibenclamide。Glibenclamide即glyburide，中文名为格列苯脲，是一种2型糖尿病治疗药物，可以结合主要定位在内质网上的包含ATP敏感的钾离子通道(K_ATP channel)的磺脲类(sulphonylurea)受体。因此荧光标记的glibenclamide就可以用作内质网特异性的荧光探针。ER-Tracker Red适用于活细胞内质网的荧光染色，但不适合用于固定细胞内质网的荧光染色。
ER-Tracker Red的分子式为C₄₄H₄₂BClF₂N₆O₇S₂，分子量为915.23，ER-Tracker Red的化学结构式参考图1。
图1.ER-Tracker Red的化学结构式。 ER-Tracker Red对于细胞的毒性极低。而传统的DiOC6(3)对ER染色的同时也对细胞有一定的毒性。
ER-Tracker Red呈红色荧光，检测时的最大激发波长为587nm，最大发射波长为615nm。ER-Tracker Red的激发光谱和发射光谱参考图2。
图2.ER-Tracker Red的激发光谱和发射光谱。 ER-Tracker Red按照后附的使用说明染色后，用甲醛等固定后染色效果可以被部分保留。ER-Tracker Red在活细胞中的染色效果参考图2。
图3.ER-Tracker Red(内质网红色荧光探针)对于NRK-52E细胞(大鼠肾小管上皮细胞)的染色效果。Mito-Tracker Green染色的NRK-52E细胞其线粒体呈现绿色荧光(图B)，ER-Tracker Red染色的NRK-52E细胞其内质网呈现红色荧光(图C)，绿色荧光、红色荧光及细胞核蓝色荧光的叠加(merge)效果见图D。其中细胞核使用Hoechst 33342 (C1027)染色。本图仅作参考，实际检测效果会因实验条件、检测仪器等的不同而存在差异。
提供了ER-Tracker Red 稀释液，使ER-Tracker Red的使用更加便捷。
按照1:1000的比例稀释，每10µl可以配制10ml ER-Tracker Red工作液；按照1:3000的比例稀释，每10µl可以配制30ml ER-Tracker Red工作液。
包装清单：

产品编号	产品名称	包装
C1041S-1	ER-Tracker Red (1mM)	20µl
C1041S-2	ER-Tracker Red稀释液	60ml
—	说明书	1份

产品编号	产品名称	包装
C1041M-1	ER-Tracker Red (1mM)	100µl
C1041M-2	ER-Tracker Red稀释液	250ml
—	说明书	1份

产品编号	产品名称	包装
C1041L-1	ER-Tracker Red (1mM)	500µl
C1041L-2	ER-Tracker Red稀释液	500ml×2
—	说明书	1份

保存条件：
-20℃保存，半年有效。ER-Tracker Red需-20℃避光保存。
注意事项：
ER-Tracker Red(1mM)在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内，可以20-25℃水浴温育片刻至全部融解后使用。对于微量的液体，每次使用前先离心数秒钟，使液体充分沉降到管底。
荧光染料均存在淬灭问题，请尽量注意避光，以减缓荧光淬灭。
需自备盖玻片和载玻片(可以向碧云天订购)。
格列本脲的药理学活性可能会影响内质网的一些功能；某些特殊细胞中磺脲类受体的可变表达可能会导致非内质网特异性染色。
ER-Tracker Red适用于活细胞内质网的荧光染色，但不适合用于固定细胞内质网的荧光染色。如果经ER-Tracker Red染色后的细胞需要进行固定操作，使用4%多聚甲醛在37℃固定2分钟。
ER-Tracker Red染色后的细胞不能用Triton X-100通透，Triton X-100通透处理会导致ER-Tracker Red的荧光染色消失。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。

使用说明：
1.ER-Tracker Red工作液的配制：
a.取少量ER-Tracker Red按照1:1000的比例加入到ER-Tracker Red 稀释液中。例如取1μl ER-Tracker Red加入到1ml ER-Tracker Red 稀释液中。混匀后即为ER-Tracker Red工作液。
b.ER-Tracker Red工作液使用前需37℃预温育。
注：工作液中ER-Tracker Red的浓度可以根据实际情况进行适当调整，推荐的稀释比例调整范围为1:1000-1:3000。为降低背景，在染色效果可以接受的范围内，建议尽量使用较低浓度的ER-Tracker Red。
2.内质网的荧光标记：
a.去除细胞培养液，用适量的溶液如HBSS with Ca²⁺ & Mg²⁺ (Hanks' Balanced Salt Solution with Ca²⁺ & Mg²⁺)洗涤生长在盖玻片上的细胞。注：HBSS with Ca²⁺ & Mg²⁺ (C0219)可以向碧云天订购；对于悬浮细胞的染色可以参考贴壁细胞的染色方法进行。
b.去除洗涤液，加入步骤1配制好的并37℃预温育的ER-Tracker Red染色工作液，与细胞37℃共孵育15-30分钟。
c.去除ER-Tracker Red染色工作液，用细胞培养液洗涤细胞1-2次。
d.随后通常用荧光显微镜或激光共聚焦显微镜进行观察。此时可观察到内质网呈明亮的强荧光染色。
e.如果经ER-Tracker Red染色后的细胞需要进行固定，可以使用4%甲醛37℃固定2分钟。固定后用适当的洗涤液洗涤2-3次，每次5分钟，随后可以进行复染或滴加适当的抗荧光淬灭封片液，最后封片观察。注意：ER-Tracker Red染色的细胞不能用Triton X-100通透，Triton X-100通透处理会导致ER-Tracker Red的荧光染色消失。

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C1033	Actin-Tracker Green (微丝绿色荧光探针)	0.2ml
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C1039-10mg	DiD (细胞膜远红外荧光探针)	10mg
C1041S/M/L	ER-Tracker Red (内质网红色荧光探针)	20μl/100μl/500μl
C1042S/M/L	ER-Tracker Green (内质网绿色荧光探针)	20μl/100μl/500μl
C1043	Golgi-Tracker Red (高尔基体红色荧光探针)	1mg
C1045S	Golgi-Tracker Green (高尔基体绿色荧光探针)	1mg
C1046	Lyso-Tracker Red (溶酶体红色荧光探针)	50μl
C1047S	Lyso-Tracker Green (溶酶体绿色荧光探针)	50μl
C1048	Mito-Tracker Green (线粒体绿色荧光探针)	50μg
C1049B-50μg	Mito-Tracker Red CMXRos (线粒体红色荧光探针)	50μg
C1049B-250μg	Mito-Tracker Red CMXRos (线粒体红色荧光探针)	50μg×5
C1050	Tubulin-Tracker Red (抗体法微管红色荧光探针)	40μl
C1051S	Tubulin-Tracker Green (抗体法微管绿色荧光探针)	40μl
C1991S	细胞膜红色荧光染色试剂盒(DiI)	200-1000次
C1993S	细胞膜绿色荧光染色试剂盒(DiO)	200-1000次
C1995S	细胞膜远红外荧光染色试剂盒(DiD)	200-1000次
C2005	JC-1	1mg
C2007	Rhodamine 123	5mg

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44. Guo C, Ma R, Liu X, Xia Y, Niu P, Ma J, Zhou X, Li Y, Sun Z

Silica nanoparticles induced endothelial apoptosis via endoplasmic reticulum stress-mitochondrial apoptotic signaling pathway.

Chemosphere. 2018 Nov;210:183-192. (IF 5.778)

45. Xu A, Tang Y, Lin W

Endoplasmic reticulum-targeted two-photon turn-on fluorescent probe for nitroreductase in tumor cells and tissues.

SPECTROCHIM ACTA A. 2018 Nov 5;204:770-776. (IF 3.232)

46. Lian YY, He HH, Zhang CZ, Li XC, Chen YH

Functional characterization of a matrix metalloproteinase 2 gene in Litopenaeus vannamei.

FISH SHELLFISH IMMUN. 2019 Jan 84:404-413. (IF 3.298)

47. Li X, Du X, Ni J

Zn2+ Aggravates Tau Aggregation and Neurotoxicity.

Int J Mol Sci. 2019 Jan 23 20(3). pii: E487. (IF 4.556)

48. Xu D, Wu L, Jiang X, Yang L, Cheng J, Chen H, Hua R, Geng G, Yang L, Li Q

SIRT2 Inhibition Results in Meiotic Arrest, Mitochondrial Dysfunction, and Disturbance of Redox Homeostasis during Bovine Oocyte Maturation.

Int J Mol Sci. 2019 Mar 18 20(6). pii: E1365. (IF 4.556)

49. Jiang YJ, Lin M, Yang T, Li RS, Huang CZ, Wang J, Li YF

Nitrogen and phosphorus doped polymer carbon dots as a sensitive cellular mapping probe of nitrite.

J Mater Chem B. 2019 Mar 28 7(12):2074-2080. (IF 5.344)

50. Chen P, Zhao M, Chen Q, Fan L, Gao F, Zhao L

Absorption Characteristics of Chitobiose and Chitopentaose in the Human Intestinal Cell Line Caco-2 and Everted Gut Sacs.

J AGR FOOD CHEM. 2019 Apr 24 67(16):4513-4523. (IF 4.192)

51. Liang XD, Zhang YN, Liu CC, Chen J, Chen XN, Sattar Baloch A, Zhou B

U18666A inhibits classical swine fever virus replication through interference with intracellular cholesterol trafficking.

Vet Microbiol. 2019 Nov 238:108436. (IF 3.03)

52. Dong C, Tu W, He M, Fu J, Kobayashi A, Konishi T, Shao C

Role of Endoplasmic Reticulum and Mitochondrion in Proton Microbeam Radiation-Induced Bystander Effect.

Radiat Res. 2020 Jan 193(1):63-72. (IF 2.657)

53. Xia Q, Wang X, Liu Y, Shen Z, Ge Z, Huang H, Li X, Wang Y

An endoplasmic reticulum-targeted two-photon fluorescent probe for bioimaging of HClO generated during sleep deprivation.

SPECTROCHIM ACTA A. 2020 Mar 15 229:117992. (IF 3.232)

54. Zhaoyang Wang, Jiaoyan Jia, Lu Wang, Feng Li, Yiliang Wang, Yuzhou Jiang, Xiaowei Song, Shurong Qin, Kai Zheng, Ju Ye, Zhe Ren, Yifei Wang, Shuhua Qi

Anti-HSV-1 activity of Aspergillipeptide D, a cyclic pentapepetide isolated from fungus Aspergillus sp. SCSIO 41501

Virol J. 2020 Mar 19;17(1):41. doi: 10.1186/s12985-020-01315-z. (IF 2.579)

55. Ru-Jia Xie, Xiao-Xia Hu, Lu Zheng, Shuang Cai, Yu-Si Chen, Yi Yang, Ting Yang, Bing Han, Qin Yang

Calpain-2 activity promotes aberrant endoplasmic reticulum stress-related apoptosis in hepatocytes

WORLD J GASTROENTERO. 2020 Apr 7;26(13):1450-1462. doi: 10.3748/wjg.v26.i13.1450. (IF 3.665)

56. Ming-Hong Sun, Xiao-Han Li, Yao Xu, Yi Xu, Zhen-Nan Pan, Shao-Chen Sun

Citrinin exposure disrupts organelle distribution and functions in mouse oocytes

Environ Res. 2020 Jun;185:109476. doi: 10.1016/j.envres.2020.109476. (IF 5.715)

57. Zhi-Fei Liu, Jian-Fei Ji, Xiao-Feng Jiang, Tong Shao, Dong-Dong Fan, Xin-Hang Jiang, Ai-Fu Lin, Li-Xin Xiang, Jian-Zhong Shao

Characterization of cGAS homologs in innate and adaptive mucosal immunities in zebrafish gives evolutionary insights into cGAS-STING pathway

FASEB J. 2020 Jun;34(6):7786-7809. doi: 10.1096/fj.201902833R. (IF 4.966)

58. Zhen-Nan Pan, Meng-Hao Pan, Ming-Hong Sun, Xiao-Han Li, Yu Zhang, Shao-Chen Sun

RAB7 GTPase regulates actin dynamics for DRP1-mediated mitochondria function and spindle migration in mouse oocyte meiosis

FASEB J. 2020 Jul;34(7):9615-9627. doi: 10.1096/fj.201903013R. (IF 4.966)

59. Fan Xiao, Meixin Gao, Junru Yang, Lingling He, Hongshan Wei

FAM172A Deletion May Enhance Hepatic Steatosis by Promoting ER Stress

DIGEST DIS SCI. 2020 Sep 18. doi: 10.1007/s10620-020-06601-y. (IF 2.751)

60. Xiuge Gao, Xiangchun Ruan, Hui Ji, Lin Peng, Yawei Qiu, Dan Yang, Xinhao Song, Chunlei Ji, Dawei Guo, Shanxiang Jiang

Maduramicin triggers methuosis-like cell death in primary chicken myocardial cells

Toxicol Lett. 2020 Oct 15;333:105-114. doi: 10.1016/j.toxlet.2020.07.025. (IF 3.569)

61. Yongnan Li, Shuodong Wu

Curcumin inhibits the proteolytic process of SREBP-2 by first inhibiting the expression of S1P rather than directly inhibiting SREBP-2 expression

Food Sci Nutr. 2020 Nov 8;9(1):209-216. doi: 10.1002/fsn3.1985. (IF 1.797)

62. Yajun Lu, Yuxiao Yang, Siqi Yang, Qianfeng Xia

Immunomodulatory action of excretory-secretory products of Angiostrongylus cantonensis in a mouse tumour model

Parasitol Res. 2020 Nov;119(11):3705-3718. doi: 10.1007/s00436-020-06872-4. (IF 1.641)

63. Qi Yang, Rongjuan Pei, Yun Wang, Yuan Zhou, Min Yang, Xinwen Chen, Jizheng Chen

ADAM15 Participates in Tick-Borne Encephalitis Virus Replication

J Virol. 2021 Jan 28;95(4):e01926-20. doi: 10.1128/JVI.01926-20. (IF 4.501)

64. Sijing Hu, Hao Zhang, Yunqiang Liu, Mohan Liu, Jingjing Li, Shunyao Liao

Whole-exome sequencing of de novo genetic variants in a Chinese family with a sporadic case of congenital nonsyndromic hearing loss

F1000Res. 2021 Feb 2;10:61. doi: 10.12688/f1000research.27739.2.

65. Yan Hui Yang, Heng Yang, Rui Fang Li, Cui Xiang Li, Lei Zeng, Chao Jie Wang, Na Li, Zhuang Luo

A Rehmannia glutinosa cinnamate 4-hydroxylase promotes phenolic accumulation and enhances tolerance to oxidative stress

Plant Cell Rep. 2021 Feb;40(2):375-391. doi: 10.1007/s00299-020-02639-4. (IF 3.825)

66. Xueling Su, Xi Yan, Xing Chen, Mei Guo, Yuxian Xia, Yueqing Cao

Calcofluor white hypersensitive proteins contribute to stress tolerance and pathogenicity in entomopathogenic fungus, Metarhizium acridum

Pest Manag Sci. 2021 Apr;77(4):1915-1924. doi: 10.1002/ps.6218. (IF 3.75)

67. Kangyong Chen, Jiayin Tian, Junya Wang, Zhao Jia, Qin Zhang, Wenji Huang, Xin Zhao, Zhipeng Gao, Qian Gao, Jun Zou

Lipopolysaccharide-induced TNFα factor (LITAF) promotes inflammatory responses and activates apoptosis in zebrafish Danio rerio

Gene. 2021 May 15;780:145487. doi: 10.1016/j.gene.2021.145487. (IF 2.984)

68. Qi Peng, Yan Liu, Xuehua Kong, Jie Xian, Lin Ye, Li Yang, Shuliang Guo, Yan Zhang, Lan Zhou, Tingxiu Xiang

The Novel Methylation Biomarker SCARA5 Sensitizes Cancer Cells to DNA Damage Chemotherapy Drugs in NSCLC

Front Oncol. 2021 Jun 4;11:666589. doi: 10.3389/fonc.2021.666589. (IF 4.848)

69. Ya-Yun Liu, Xiao-Dong Liang, Chun-Chun Liu, Yan Cheng, Huan Chen, Abdul Sattar Baloch, Jin Zhang, Yun Young Go, Bin Zhou

Fatty Acid Synthase Is Involved in Classical Swine Fever Virus Replication by Interaction with NS4B

J Virol. 2021 Aug 10;95(17):e0078121. doi: 10.1128/JVI.00781-21. (IF 4.501)

70. Jinming Zhang, Wenshan Zhong, Yuanyuan Liu, Weimou Chen, Ye Lu, Zhaojin Zeng, Yujie Qiao, Haohua Huang, Xuan Wan, Wei Li, Xiaojing Meng, Fei Zou, Shaoxi Cai, Hangming Dong

Extracellular HSP90α Interacts With ER Stress to Promote Fibroblasts Activation Through PI3K/AKT Pathway in Pulmonary Fibrosis

Front Pharmacol. 2021 Aug 23;12:708462. doi: 10.3389/fphar.2021.708462. (IF 4.225)

71. Rongjin Luo, Shuai Li, Gaocai Li, Saideng Lu, Weifeng Zhang, Hui Liu, Jie Lei, Liang Ma, Wencan Ke, Zhiwei Liao, Bingjin Wang, Yu Song, Kun Wang, Yukun Zhang, Cao Yang

FAM134B-Mediated ER-phagy Upregulation Attenuates AGEs-Induced Apoptosis and Senescence in Human Nucleus Pulposus Cells

Oxid Med Cell Longev. 2021 Aug 5;2021:3843145. doi: 10.1155/2021/3843145. (IF 5.076)

72. Jinglun Zhang, Qian Wu, Chengcheng Yin, Xiaoshi Jia, Zifan Zhao, Xiaoxin Zhang, Guohua Yuan, Hao Hu, Qin Zhao

Sustained calcium ion release from bioceramics promotes CaSR-mediated M2 macrophage polarization for osteoinduction

J Leukoc Biol. 2021 Sep;110(3):485-496. doi: 10.1002/JLB.3MA0321-739R.

73. Lin Meng, Hongmei Hu, Zhiqiang Liu, Luyao Zhang, Qingrui Zhuan, Xue Li, Xiangwei Fu, Shien Zhu, Yunpeng Hou

The Role of Ca2 + in Maturation and Reprogramming of Bovine Oocytes: A System Study of Low-Calcium Model

Front Cell Dev Biol. 2021 Oct 26;9:746237. doi: 10.3389/fcell.2021.746237. (IF 5.201)

74. Zhihao Liu, Xiyun Bian, Wenbo Gao, Jing Su, Chuanrui Ma, Xiaolin Xiao, Tian Yu, Han Zhang, Xiaozhi Liu, Guanwei Fan

Rg3 promotes the SUMOylation of SERCA2a and corrects cardiac dysfunction in heart failure

Pharmacol Res. 2021 Oct;172:105843. doi: 10.1016/j.phrs.2021.105843. (IF 5.893)

75. Yi-Ming Li, Shao-Yang Zhao, Huan-Huan Zhao, Bao-Hua Wang, Sai-Mei Li

Procyanidin B2 Alleviates Palmitic Acid-Induced Injury in HepG2 Cells via Endoplasmic Reticulum Stress Pathway

Evid Based Complement Alternat Med. 2021 Dec 16;2021:8920757. doi: 10.1155/2021/8920757.

76. Lin Lei, Wenwen Gao, Juan J Loor, Ahmad Aboragah, Zhiyuan Fang, Xiliang Du, Min Zhang, Yuxiang Song, Guowen Liu, Xinwei Li

Reducing hepatic endoplasmic reticulum stress ameliorates the impairment in insulin signaling induced by high levels of β-hydroxybutyrate in bovine hepatocytes

J Dairy Sci. 2021 Dec;104(12):12845-12858. doi: 10.3168/jds.2021-20611. (IF 3.333)

77. Shaojuan Song, Xin Xia, Jiajia Qi, Xiaopei Hu, Qian Chen, Jiang Liu, Ning Ji, Hang Zhao

Silmitasertib-induced macropinocytosis promoting DDP intracellular uptake to enhance cell apoptosis in oral squamous cell carcinoma

Drug Deliv. 2021 Dec;28(1):2480-2494. doi: 10.1080/10717544.2021.2000677. (IF 4.902)

78. Hao Zhao, Yue Xu, Xinlei Song, Qingchen Zhang, Yajie Wang, Haiyan Yin, Xiaohui Bai, Jianfeng Li

Cisplatin induces damage of auditory cells: Possible relation with dynamic variation in calcium homeostasis and responding channels

Eur J Pharmacol. 2022 Jan 5:914:174662. doi: 10.1016/j.ejphar.2021.174662. (IF 3.263)

79. Jianzhao Liao, Zhuoying Hu, Quanwei Li, Hongji Li, Weijin Chen, Haihua Huo, Qingyue Han, Hui Zhang, Jianying Guo, Lianmei Hu, Jiaqiang Pan, Ying Li, Zhaoxin Tang

Endoplasmic Reticulum Stress Contributes to Copper-Induced Pyroptosis via Regulating the IRE1α-XBP1 Pathway in Pig Jejunal Epithelial Cells

J Agric Food Chem. 2022 Feb 2;70(4):1293-1303. doi: 10.1021/acs.jafc.1c07927.

80. Meng-Meng Shan, Yuan-Jing Zou, Zhen-Nan Pan, Hao-Lin Zhang, Yi Xu, Jia-Qian Ju, Shao-Chen Sun

Kinesin motor KIFC1 is required for tubulin acetylation and actin-dependent spindle migration in mouse oocyte meiosis

Development. 2022 Mar 1;149(5):dev200231. doi: 10.1242/dev.200231. (IF 5.611)

81. Lin Zhu, Bin Li, Dongqin Chen, Ning Chen, Le Xu, Qinjin Li, Xiaodong Chen

sSTEAP4 regulates cellular homeostasis and improves high-fat-diet-caused oxidative stress in hepatocytes

Life Sci. 2022 May 1:296:120438. doi: 10.1016/j.lfs.2022.120438. (IF 3.647)

82. Fangjiao Lv, Yang Xu, Dean W Gabriel, Xue Wang, Ning Zhang, Wenxing Liang

Quantitative Proteomic Analysis Reveals Important Roles of the Acetylation of ER-Resident Molecular Chaperones for Conidiation in Fusarium oxysporum

Mol Cell Proteomics. 2022 May;21(5):100231. doi: 10.1016/j.mcpro.2022.100231. (IF 4.87)

83. Yu-Shen Luo, Quan-Kuo He, Ming-Xin Sun, Feng-Xin Qiao, Yue-Cen Liu, Chang-Long Xu, Zhi-Ran Xu, Si-Cheng Zhao, Hai-Long Wang, Zhong-Quan Qi, Yu Liu

Acrylonitrile exposure triggers ovarian inflammation and decreases oocyte quality probably via mitochondrial dysfunction induced apoptosis in mice

Chem Biol Interact. 2022 Jun 1:360:109934. doi: 10.1016/j.cbi.2022.109934.

84. Shuanghang Liu, Tingxian Deng, Liping Hua, Xinzhe Zhao, Hanxiao Wu, Peihao Sun, Mingxiao Liu, Shujun Zhang, Liguo Yang, Aixin Liang

Novel functional mutation of the PDIA3 gene affects milk composition traits in Chinese Holstein cattle

J Dairy Sci. 2022 Jun;105(6):5153-5166. doi: 10.3168/jds.2021-21035. (IF 3.333)

85. Yunyi Liu, Juan Li, Hailong Ou, Dan Qi, Bei Hu, Yuxi Xu, Jian Hu, Yi Xiong, Luling Xia, Jason H Huang, Xiaoxiao Hu, Erxi Wu

Identification of new aptamer BC-3 targeting RPS7 from rapid screening for bladder carcinoma

Genes Dis. 2022 Aug 3;10(5):2137-2150. doi: 10.1016/j.gendis.2022.07.002.

86. Huidi Xie, Yang Shi, Ying Zhou, Hongfang Liu

TMBIM6 promotes diabetic tubular epithelial cell survival and albumin endocytosis by inhibiting the endoplasmic reticulum stress sensor, IRE1α

Mol Biol Rep. 2022 Oct;49(10):9181-9194. doi: 10.1007/s11033-022-07744-z. (IF 1.402)

87. Yue Li, Ran Yao, Miao Ren, Ke Yuan, Yuwei Du, Yuan He, Haiquan Kang, Shengnan Yuan, Wen Ju, Jianlin Qiao, Kailin Xu, Lingyu Zeng

Liposomes trigger bone marrow niche macrophage "foam" cell formation and affect hematopoiesis in mice

J Lipid Res. 2022 Oct;63(10):100273. doi: 10.1016/j.jlr.2022.100273. (IF 4.483)

88. Yan Li, Hong-Ying Li, Jun Shao, Lingpeng Zhu, Tian-Hua Xie, Jiping Cai, Wenjuan Wang, Meng-Xia Cai, Zi-Li Wang, Yong Yao, Ting-Ting Wei

GRP75 Modulates Endoplasmic Reticulum-Mitochondria Coupling and Accelerates Ca2+-Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy

Biomolecules. 2022 Nov 29;12(12):1778. doi: 10.3390/biom12121778. (IF 4.082)

89. Han Zhang, Yunfeng Tian, Xiaoya Yuan, Fei Xie, Siqi Yu, Jiayou Cai, Bin Sun, Changliang Shan, Weicheng Zhang

Site-directed late-stage diversification of macrocyclic nannocystins facilitating anticancer SAR and mode of action studies

RSC Med Chem. 2022 Dec 22;14(2):299-312. doi: 10.1039/d2md00393g.

90. Zhao-Ran Wang, Ting-Jian Zhang, Qiu-Yin Wang, En-Yu Xu, Xu Zhang, Zhen-Hao Zhang, Peng-Fei Lu, Hai-Yang Zhao, Lin Wang, Fan-Hao Meng

(E)-2-styrylanthracene-9,10-dione derivatives as novel fluorescent probes: synthesis, photophysical properties and application in mitochondria imaging

Spectrochim Acta A Mol Biomol Spectrosc. 2023 Feb 5:286:121988. doi: 10.1016/j.saa.2022.121988.

91. Chan Li, Hui Zhang, Hao Wu, Ruoyu Li, Dongxu Wen, Yaju Tang, Zhen Gao, Rui Xu, Sihai Lu, Qiang Wei, Xiaoe Zhao, Menghao Pan, Baohua Ma

Intermittent fasting reverses the declining quality of aged oocytes

Free Radic Biol Med. 2023 Feb 1:195:74-88. doi: 10.1016/j.freeradbiomed.2022.12.084.

92. Huiduo Li, Yanan Jing, Xiaoya Qu, Jinyi Yang, Pengge Pan, Xinrui Liu, Hui Gao, Xiuying Pei, Cheng Zhang, Yanzhou Yang

The Activation of Reticulophagy by ER Stress through the ATF4-MAP1LC3A-CCPG1 Pathway in Ovarian Granulosa Cells Is Linked to Apoptosis and Necroptosis

Int J Mol Sci. 2023 Feb 1;24(3):2749. doi: 10.3390/ijms24032749.

93. Jielin Tang, Chonghui Xu, Muqing Fu, Canyu Liu, Xianwen Zhang, Wei Zhang, Rongjuan Pei, Yun Wang, Yuan Zhou, Jizheng Chen, Zhichao Miao, Guangjin Pan, Qi Yang, Xinwen Chen

Sterile 20-like kinase 3 promotes tick-borne encephalitis virus assembly by interacting with NS2A and prM and enhancing the NS2A-NS4A association

J Med Virol. 2023 Mar;95(3):e28610. doi: 10.1002/jmv.28610.

94. Yueqi Wang, Changjian Li, Jiaming Zhuo, Hui Hui, Bing Zhou, Jie Tian

The Detection of Divalent Iron and Reactive Oxygen Species During Ferroptosis with the Use of a Dual-Reaction Turn-On Fluorescent Probe

Mol Imaging Biol. 2023 Apr;25(2):423-434. doi: 10.1007/s11307-022-01774-6.

95. Xing Xue, Xiulin Wu, Lijuan Liu, Lianzhong Liu, Fan Zhu

ERVW-1 Activates ATF6-Mediated Unfolded Protein Response by Decreasing GANAB in Recent-Onset Schizophrenia

Viruses. 2023 May 31;15(6):1298. doi: 10.3390/v15061298.

96. Yanlong Guan, Guanxiao Chang, Jinjie Zhao, Qia Wang, Jiali Qin, Mengmeng Tang, Shuanghua Wang, Lan Ma, Jianchao Ma, Guiling Sun, Yun Zhou, Jinling Huang

Parallel evolution of two AIM24 protein subfamilies and their conserved functions in ER stress tolerance in land plants

Plant Commun. 2023 May 8;4(3):100513. doi: 10.1016/j.xplc.2022.100513.

97. Si-Le Wu, Jia-Qian Ju, Yi-Ming Ji, Hao-Lin Zhang, Yuan-Jing Zou, Shao-Chen Sun

Exposure to acrylamide induces zygotic genome activation defects of mouse embryos

Food Chem Toxicol. 2023 May:175:113753. doi: 10.1016/j.fct.2023.113753.

98. Fangyuan Zhou, Haiyang Gao, Luorui Shang, Jinxiao Li, Mengqi Zhang, Shuhan Wang, Runze Li, Lin Ye, Shenglan Yang

Oridonin promotes endoplasmic reticulum stress via TP53-repressed TCF4 transactivation in colorectal cancer

J Exp Clin Cancer Res. 2023 Jun 19;42(1):150. doi: 10.1186/s13046-023-02702-4.

99. Yashi Wang, Lin Xiong, Ziyan Dong, Kaixin Ran, Wenjing Bai, Ziyi Mo, Kexin Huang, Yunxia Ye, Yuan Tao, Sheng Yin, Man Li, Qin He

Autophagy-Interfering Nanoboat Drifting along CD44-Golgi-ER Flow as RNAi Therapeutics for Hepatic Fibrosis

ACS Appl Mater Interfaces. 2023 Jun 21;15(24):28941-28953. doi: 10.1021/acsami.3c03416.

100. Feng-Xin Qiao, Ming-Xin Sun, Zhi-Ran Xu, Yue-Cen Liu, Yan-Zhu Chen, Hai-Long Wang, Zhong-Quan Qi, Chang-Long Xu, Yu Liu

Chloroacetonitrile exposure induces endoplasmic reticulum stress and affects spindle assembly in mouse oocytes

Food Chem Toxicol. 2023 Jun:176:113736. doi: 10.1016/j.fct.2023.113736.

101. Weixiang Bian, Hua Jiang, Luxia Yao, Wanyu Hao, Lianfeng Wu, Xu Li

A spatially defined human Notch receptor interaction network reveals Notch intracellular storage and Ataxin-2-mediated fast recycling

Cell Rep. 2023 Jul 25;42(7):112819. doi: 10.1016/j.celrep.2023.112819.

102. Yilong Shi, Xiaoxue Zou, Xianghui Zheng, Yimin Wu, Jiahuai Han, Shoufa Han

Sensitive imaging of Endoplasmic reticulum (ER) autophagy with an acidity-reporting ER-Tracker

Autophagy. 2023 Jul;19(7):2015-2025. doi: 10.1080/15548627.2023.2165759.

103. Yin-Zheng Wang, Yan-Xiang Lin, Qi Liu, Jing Liu, Spencer C H Barrett

A new type of cell related to organ movement for selfing in plants

Natl Sci Rev. 2023 Aug 10;10(9):nwad208. doi: 10.1093/nsr/nwad208.

104. Leqing Zhu, Xichun Xia, Guangqiang Li, Chuyun Zhu, Qingqing Li, Baocheng Wang, Nan-Xi Shi, Zhiwei Lei, Shuxian Yang, Zhanpeng Zhang, Haishan Li, Jingyi Tan, Zonghua Liu, Qiong Wen, Hui Zhong, Xue-Jia Lin, Guodong Sun, Xiucong Bao, Qian Wang, Liehua Deng, Lianghua Bin, Guangchao Cao, Zhinan Yin

SLC38A5 aggravates DC-mediated psoriasiform skin inflammation via potentiating lysosomal acidification

Cell Rep. 2023 Aug 29;42(8):112910. doi: 10.1016/j.celrep.2023.112910.

105. Yongqi Yue, Yuhe Wang, Chenglong Wen, Yingying Meng, Ying Peng, Xiao Li

Lnc-Malat1 promotes slow myofiber-type transformation through sponging miR-129-5p in C2C12 myotubes

Exp Cell Res. 2023 Oct 1;431(1):113761. doi: 10.1016/j.yexcr.2023.113761.

106. Shuibing Liu, Jintao Wu, Wentao Zhang, Hongxia Jiang, Yanan Zhou, Jing Liu, Huirong Mao, Sanfeng Liu, Biao Chen

Whole-Transcriptome RNA Sequencing Uncovers the Global Expression Changes and RNA Regulatory Networks in Duck Embryonic Myogenesis

Int J Mol Sci. 2023 Nov 16;24(22):16387. doi: 10.3390/ijms242216387.

107. Jie Liu, Dandan Zhang, Zihui Yang, Yiming Hao, Zongwei Wang, Jing Wang, Ziyuan Wang

Wheat Alkylresorcinols Modulate Glucose Homeostasis through Improving GLP-1 Secretion in High-Fat-Diet-Induced Obese Mice

J Agric Food Chem. 2023 Nov 1;71(43):16125-16136. doi: 10.1021/acs.jafc.3c04664.

108. Qiuyue Zheng, Fengying Gao, Zhigang Liu, Chengfei Sun, Junjian Dong, Hetong Zhang, Xiaoli Ke, Maixin Lu

Nile tilapia TBK1 interacts with STING and TRAF3 and is involved in the IFN-β pathway in the immune response

Fish Shellfish Immunol. 2023 Nov:142:109125. doi: 10.1016/j.fsi.2023.109125.

109. Zhu Zhu, Ruixue Liao, Yang Shi, Jingyan Li, Jimin Cao, Bin Liao, Jianming Wu, Guang Li

Polystyrene nanoplastics induce apoptosis of human kidney proximal tubular epithelial cells via oxidative stress and MAPK signaling pathways

Environ Sci Pollut Res Int. 2023 Nov;30(51):110579-110589. doi: 10.1007/s11356-023-30155-x.

110. Yingbo Liang, Fanwei Meng, Xia Zhao, Xinyi He, Jun Liu

OsHLP1 is an endoplasmic-reticulum-phagy receptor in rice plants

Cell Rep. 2023 Dec 26;42(12):113480. doi: 10.1016/j.celrep.2023.113480.

111. Haibing Xiao, Yan Qu, Haolin Li, Yi Zhang, Mintian Fei, Chaozhao Liang, Hongmei Yang, Xiaoping Zhang

HIF-2α/LINC02609/APOL1-mediated lipid storage promotes endoplasmic reticulum homeostasis and regulates tumor progression in clear-cell renal cell carcinoma

J Exp Clin Cancer Res. 2024 Jan 23;43(1):29. doi: 10.1186/s13046-023-02940-6.

112. Bingqing Hui, Chenchen Zhou, Yetao Xu, Rui Wang, Yuwen Dong, Yirui Zhou, Jie Ding, Xiao Zhang, Jian Xu, Yanhong Gu

Exosomes secreted by Fusobacterium nucleatum-infected colon cancer cells transmit resistance to oxaliplatin and 5-FU by delivering hsa_circ_0004085

J Nanobiotechnology. 2024 Feb 15;22(1):62. doi: 10.1186/s12951-024-02331-9.

113. Qiuyue Zheng, Zhigang Liu, Chengfei Sun, Junjian Dong, Hetong Zhang, Xiaoli Ke, Fengying Gao, Maixin Lu

Molecular characterization, expression and functional analysis of TAK1, TAB1 and TAB2 in Nile tilapia (Oreochromis niloticus)

Fish Shellfish Immunol. 2024 Feb:145:109359. doi: 10.1016/j.fsi.2024.109359.

114. Lian Wang, Ning Luo, Jihui Zhu, Zubaidan Sulaiman, Wenhan Yang, Ke Hu, Guihai Ai, Weihong Yang, Xiaowen Shao, Shengkai Jin, Xue Zhang, Yantao Fan, Dan Deng, Zhongping Cheng, Zhengliang Gao

Peritoneal adipose stem cell-derived extracellular vesicles mediate the regulation of ovarian cancer cell proliferation and migration through EGFR-NF-κB signaling

Genes Dis. 2024 Mar 28;12(2):101283. doi: 10.1016/j.gendis.2024.101283.

115. Lin-Lin Hu, Mei-Hua Liao, Ya-Xi Liu, Chun-Hua Xing, Lan-Lan Nong, Feng-Lian Yang, Shao-Chen Sun

Loss of AMPK activity induces organelle dysfunction and oxidative stress during oocyte aging

Biol Direct. 2024 Apr 23;19(1):29. doi: 10.1186/s13062-024-00471-4.

116. Jing-Cai Liu, Zhen-Nan Pan, Jia-Qian Ju, Yuan-Jing Zou, Meng-Hao Pan, Yue Wang, Xin Wu, Shao-Chen Sun

Kinesin KIF3A regulates meiotic progression and spindle assembly in oocyte meiosis

Cell Mol Life Sci. 2024 Apr 8;81(1):168. doi: 10.1007/s00018-024-05213-3.

117. Lei Zhu, Yilin Shi, Zhelong Feng, Dingyi Yuan, Shiduo Guo, Yuxia Wang, Haowen Shen, Yan Li, Fang Yan, Yajing Wang

Fatostatin promotes anti-tumor immunity by reducing SREBP2 mediated cholesterol metabolism in tumor-infiltrating T lymphocytes

Eur J Pharmacol. 2024 May 15:971:176519. doi: 10.1016/j.ejphar.2024.176519.

118. Peng Xie, Qiao Jin, Lingpu Zhang, Hanchen Zhang, Nicolás Montesdeoca, Johannes Karges, Haihua Xiao, Xinzhan Mao, Haiqin Song, Kun Shang

Endowing Pt(IV) with Perfluorocarbon Chains and Human Serum Albumin Encapsulation for Highly Effective Antitumor Chemoimmunotherapy

ACS Nano. 2024 May 28;18(21):13683-13695. doi: 10.1021/acsnano.4c01352.

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Acetate Alleviates Gut Microbiota Depletion-Induced Retardation of Skeletal Muscle Growth and Development in Young Mice

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