碧云天生物技术-Caspase抑制剂Z-VAD-FMK(C1202-5mg)

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Caspase抑制剂Z-VAD-FMK

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产品编号: C1202-5mg

产品包装:5mg

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20mM×0.02ml 20mM×0.1ml 5mg

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价格: ¥ 1792.00

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产品编号	产品名称	产品包装	产品价格
C1202-0.02ml	Caspase抑制剂Z-VAD-FMK	20mM×0.02ml	372.00元
C1202-0.1ml	Caspase抑制剂Z-VAD-FMK	20mM×0.1ml	725.00元
C1202-5mg	Caspase抑制剂Z-VAD-FMK	5mg	1792.00元

Caspase抑制剂Z-VAD-FMK(Caspase Inhibitor Z-VAD-FMK)是一种可以穿透细胞膜的泛Caspase抑制剂(Cell permeable pan caspase inhibitor)，可以抑制由Caspase激活导致的细胞凋亡。
本Caspase抑制剂Z-VAD-FMK是一种不可逆的Caspase广普抑制剂，分子式为Z-Val-Ala-Asp-CH₂F，即C₂₁H₂₈FN₃O₇，分子量为453.5，纯度>95%。
Caspase抑制剂Z-VAD-FMK是一种最常用的细胞凋亡抑制剂，常用于观察特定的细胞凋亡是否通过Caspase激活来介导。
Caspase抑制剂Z-VAD-FMK不仅可以穿透细胞膜抑制细胞内的Caspase，也可以用于抑制体外纯化或粗抽提的Caspase。
本Caspase抑制剂Z-VAD-FMK 20mM包装产品配制在DMSO中，可以直接使用。5mg包装为粉末装。
包装清单：

产品编号	产品名称	包装
C1202-0.02ml	Caspase抑制剂Z-VAD-FMK	20mM×0.02ml
C1202-0.1ml	Caspase抑制剂Z-VAD-FMK	20mM×0.1ml
C1202-5mg	Caspase抑制剂Z-VAD-FMK	5mg
—	说明书	1份

保存条件：
-20℃保存，一年有效。
注意事项：
如果每次使用量少，使用次数较多，请适当分装。反复冻融会影响本抑制剂的使用效果。
如果希望适当稀释后再分装保存，请使用DMSO进行稀释。
本Caspase抑制剂Z-VAD-FMK在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内，可以20-25℃水浴温育片刻至全部融解后使用。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。

使用说明：
1. Caspase抑制剂Z-VAD-FMK在终浓度为20μM时可以非常显著地抑制大多数细胞凋亡诱导剂诱导的细胞凋亡。Caspase抑制剂Z-VAD-FMK抑制细胞凋亡的常见有效浓度范围为5-100μM。
2. Caspase抑制剂Z-VAD-FMK用于抑制细胞凋亡时至少需要和细胞凋亡诱导剂同时加入，或者需在细胞凋亡诱导剂加入前10-30分钟加入到细胞培养液中，或参考相关文献进行。
3. 如果用于抑制纯化或粗抽提的Caspase，推荐Caspase抑制剂Z-VAD-FMK与待测样品预孵育10-20分钟，再进行后续测定。

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