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| 产品编号 | 产品名称 | 产品包装 | 产品价格 |
| SM8040-10mM | 没食子酸(98%, HPLC) | 10mM×0.2ml | 68.00元 |
| SM8040-25mg | 没食子酸(98%, HPLC) | 25mg | 50.00元 |
| SM8040-100mg | 没食子酸(98%, HPLC) | 100mg | 170.00元 |
| 中文名 | 没食子酸 |
| 英文名 | Gallic acid |
| 中文别名 | - |
| 英文别名 | 3,4,5-Trihydroxybenzoic acid |
| 来源 | 余甘子Phyllanthus emblica Linn.；山茱萸Cornus officinalis Sieb. et Zucc.；掌叶大黄Rheum palmatum L. |
| 化合物类型 | 酚类(Phenols) |
| 化学式 | C7H6O5 |
| 分子量 | 170.12 |
| CAS号 | 149-91-7 |
| 纯度 | 98%, HPLC |
| 溶剂/溶解度 | DMSO: 100 mg/ml (587.82 mM) |
| 溶液配制 | 2mg加入1.18ml DMSO，或者每1.70mg加入1ml DMSO，配制成10mM溶液。 |
| 产品描述 | Gallic acid (3,4,5-Trihydroxybenzoic acid) is a natural polyhydroxyphenolic compound and an free radical scavenger to inhibit cyclooxygenase-2 (COX-2)1. Gallic acid has various activities, such as antimicrobial, antioxidant, antimicrobial, anti-inflammatory, and anticancer activities. | ||||
| 信号通路 | - | ||||
| 靶点 | COX-2 | - | - | - | - |
| IC50 | - | - | - | - | - |
| 体外研究 | Gallic acid is an antioxidant which can inhibit both COX-2. After 18 h treatment with Gallic acid, the number of viable neutrophils is dramatically decreased from 40.3% to 27.7%, highly comparable with 26.4% for untreated neutrophils. Gallic acid fails to attenuate isoproterenol-induced myocytolysis. | ||||
| 体内研究 | The food intake (2.6±0.08 g/day, p=0.69) and the body weight (2.5±0.69 g, p=0.76) of the Gallic acid group do not differ significantly from those of the control group (food intake; 2.41±0.14 g/day and the body weight; 2.83±0.84 g/day). The blood glucose tolerance in the Gallic acid group is significantly improved after 2 weeks of treatment. The blood glucose tolerance of the Gallic acid group after a treatment period of 2 weeks is also significantly better than that of the control group at 90 and 120 min ( p<0.05). The serum triglyceride concentration in the Gallic acid group (0.67±0.03 mM, p<0.05) is significantly reduced relative to that of the control group (1.08±0.20 mM). The total cholesterol concentration is similar in the control (3.19±0.27 mM) and Gallic acid (3.01±0.18 mM) groups. | ||||
| 临床实验 | N/A | ||||
1.Amaravani M, et al. Springerplus. 2012,1(1):58.
2.Bak EJ, et al. Scand J Clin Lab Invest. 2013,73(8):607-14.
3.Cheng Y, et al. Oxid Med Cell Longev. 2015:434052.
包装清单：| 产品编号 | 产品名称 | 包装 |
| SM8040-10mM | 没食子酸(98%, HPLC) | 10mM×0.2ml |
| SM8040-25mg | 没食子酸(98%, HPLC) | 25mg |
| SM8040-100mg | 没食子酸(98%, HPLC) | 100mg |
| － | 说明书 | 1份 |
-20℃保存，至少一年有效。固体粉末4℃保存，至少一个月有效。如果溶于非DMSO溶剂，建议分装后-80℃保存，预计6个月内有效。
注意事项：本产品可能对人体有一定的毒害作用，请注意适当防护，以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
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