碧云天生物技术-总一氧化氮检测试剂盒(S0024)

试剂

技术服务

订货电话

400-1683301

800-8283301

电话订货时间:

工作日9:00-17:00

订货邮件

order@beyotime.com

订货QQ

4001683301

订货须知

订单下载

碧云天订单.xls

资源下载

试剂> 信号转导> 信号小分子检测> 一氧化氮相关

总一氧化氮检测试剂盒

一键复制产品信息

产品编号: S0024

代为检测》

产品包装:200次

选择包装

50次 200次

数

量

说明书下载

价格: ¥ 1850.00

加入购物车

				产品简介
			
				使用说明
			
				产品文件
			
				相关产品
			
				相关论文
			
				产品问答

产品编号	产品名称	产品包装	产品价格
S0023	总一氧化氮检测试剂盒	50次	588.00元
S0024	总一氧化氮检测试剂盒	200次	1850.00元

总一氧化氮检测试剂盒(Total Nitric Oxide Assay Kit, 即Nitrate/Nitrite Assay Kit)采用了硝酸盐还原酶(Nitrate reductase)还原硝酸盐(nitrate)为亚硝酸盐(nitrite)，然后通过经典的Griess reagent检测亚硝酸盐，从而测定出总一氧化氮。一氧化氮本身极不稳定，在细胞内很快代谢为硝酸盐(Nitrate)和亚硝酸盐(Nitrite)，通过上述方法检测出硝酸盐和亚硝酸盐的总量，就可以推算出总的一氧化氮的量。
本试剂盒采用了NADPH依赖性硝酸盐还原酶(NADPH dependent nitrate reductase)。高浓度的NADPH会干扰后续的检测，消除NADPH的一种常用方法就是使用Lactate dehydrogenase(LDH)清除NADPH。本试剂盒采用了LDH清除NADPH的方法，使检测结果更加准确。
对亚硝酸盐的检测下限达到2微摩尔/升，在2-80微摩尔/升的范围内有很好的线性关系。浓度过高的样品可以适当稀释后再进行检测。
样品范围广，可以检测细胞裂解液、组织裂解液、细胞或组织的培养液、血清、血浆或尿液等中一氧化氮的含量。酚红和10%血清对测定无明显干扰。
样品需要量少。根据样品中一氧化氮的浓度不同，仅需0-60微升样品。
检测速度快，仅需约80分钟即可完成检测。
本试剂盒采用了间接的一氧化氮检测方法，如需检测细胞内实际的一氧化氮水平，可以采用碧云天生产的DAF-FM DA(NO荧光探针)(S0019)。
包装清单：

产品编号	产品名称	包装
S0024-1	样品稀释液	15ml
S0024-2	NADPH	5mg
S0024-3	FAD	1.1ml X2
S0024-4	Nitrate Reductase	1ml
S0024-5	LDH Buffer	1.1ml X2
S0024-6	LDH	1ml X2
S0024-7	NaNO₂(1M)	1ml
S0024-8	Griess Reagent I	12ml
S0024-9	Griess Reagent II	12ml
—	说明书	1份

保存条件：
-20℃保存，一年有效。NADPH，Nitrate Reductase，NaNO₂ (1M)，Griess Reagent I和Griess Reagent II需避光保存。NADPH配制成溶液后必须分装并-70℃保存。
注意事项：
RPMI 1640等含有较高浓度硝酸盐的培养液容易对本试剂盒的检测产生干扰，请尽量避免。必需使用RPMI 1640培养液时，在检测一氧化氮前必需先换成其他适当培养液例如DMEM、MEM、F12等，或换成HBSS或PBS等。
推荐选购碧云天生产的细胞与组织裂解液(一氧化氮检测用)(S3090)用于细胞或组织样品的裂解。也可以自行选择适当方式制备细胞或组织样品的裂解液用于总一氧化氮的检测，但需注意自行选择的方式可能会干扰试剂盒检测时的酶反应而影响检测效果。检测细胞或组织的培养液、血清、血浆或尿液中的总一氧化氮含量时，不需要选购S3090。S3090裂解获得的样品还可以用于蛋白浓度的检测以及Western印迹检测，但需注意S3090中不含蛋白酶和磷酸酯酶抑制剂。
检测反应必须避光进行。
由于检测过程中有还原反应，凡是影响还原反应的氧化或还原试剂要注意避免，例如常用的还原剂DTT和巯基乙醇。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。

使用说明：
1. 样品处理：
含有高浓度蛋白的样品例如血清、含有高浓度血清的细胞培养液，在加入Griess Reagent I后可能会产生沉淀。可以取50微升样品，加入50微升Griess Reagent I进行测试，观察是否产生沉淀。如果产生沉淀，则可以把样品沸水浴加热5分钟，以变性蛋白，然后12,000g离心5分钟，取上清用于后续的测定。对于细胞或组织样品可以用碧云天生产的细胞与组织裂解液(一氧化氮检测用)(S3090)进行裂解。对于尿液样品，通常需要用水稀释10-50倍后检测。不宜使用肝素抗凝的血浆，肝素抗凝的血浆在和Griess Reagent反应时会产生沉淀。
2. 稀释标准品：
用制备或稀释样品时所使用的溶液把1M NaNO2稀释成2、5、10、20、40、60、80微摩尔/升。例如样品为使用S3090细胞裂解液，则宜使用S3090稀释标准品；样品为细胞培养液，则用该培养液稀释标准品。如果样品为血清，则可以使用本试剂盒提供的样品稀释液(S0024-1)或简单地使用PBS、生理盐水等适当溶液稀释标准品。稀释的标准品宜现配现用，不宜冻存后使用。
3. 试剂的准备：
a. 加约1ml双蒸水或Milli-Q级纯水至5mg NADPH中，颠倒混匀溶解后，再用双蒸水或Milli-Q级纯水定容至3ml，配制成2mM NADPH，除立即使用的部分外，其余NADPH溶液必须立即分装后-70℃冻存。
b. FAD已经配制在适当溶液中。FAD可以适当分装后-20℃或-70℃保存。
c. Nitrate Reductase和LDH在临用前取出，并放置在冰浴上使用(注意在使用完毕后立即-20℃保存)，试剂盒中的其余各种试剂在溶解后保存在冰浴上。Griess Reagent I和Griess Reagent II 在使用前需达到室温。
4. 参考下表依次加入标准品、样品和检测试剂并进行相应检测：

	空白对照	标准品	样品
标准品	－	60微升	－
样品	－	－	x微升
用于样品稀释的溶液	60微升	－	(60-x)微升
NADPH(2mM)	5微升	5微升	5微升
FAD	10微升	10微升	10微升
Nitrate Reductase	5微升	5微升	5微升
混匀后，37℃孵育30分钟
LDH Buffer	10微升	10微升	10微升
LDH	10微升	10微升	10微升
混匀后，37℃孵育30分钟
Griess Reagent I	50微升	50微升	50微升
Griess Reagent II	50微升	50微升	50微升
混匀后，室温(20-30℃)孵育10分钟后测定A540

注意事项：
a. 反应必须避光进行。如果使用96孔板进行检测，可以使用铝箔纸包裹96孔板进行避光。
b. 样品的用量上限为60微升，血清、血浆或组织匀浆液通常使用40微升就足够了。样品不足60微升时，不同样品之间的体积需要保持一致，体积不足的部分用制备或稀释样品时所使用的溶液补足。标准品可以参考上表使用60微升。
c. 可以同时设置加入200微升水或PBS的2-3个孔为阴性对照，这2-3个孔仅仅加入水或PBS，不再加入任何其他试剂。
d. 第一部分37℃孵育30分钟后，直接参考上表依次加入LDH Buffer和LDH，并进行后续孵育。
e. 第二部分37℃孵育30分钟后，直接参考上表依次加入Griess Reagent I和Griess Reagent II。加入Griess Reagent I后需要轻轻混匀。
f. 每次混匀后，可以1000-3000g离心数秒，把液体沉淀到管底。同时需避免各检测孔中产生气泡，以免气泡干扰检测结果。
g. 检测时，如无540nm滤光片，520-560nm的滤光片也可以使用。如无酶标仪或合适的滤光片，也可以通过数码相机拍照后在适当图形软件中进行定量分析，并确定样品中一氧化氮的浓度。拍照比色时标准品需要更为精细的浓度梯度。
5. 根据标准品曲线计算出样品中一氧化氮的浓度。
6. 标准曲线示例见图1，供参考。实际测定时，由于反应条件、试剂盒批次的不同等因素，会导致检测结果与示例数据存在一定差异。
常见问题：
1．检测结果标准曲线良好，但样品的吸光度很低，和空白对照接近。
标准曲线良好说明检测方法和检测试剂盒基本上没有问题，样品吸光度低说明样品中一氧化氮含量很低。可以采取的办法是：(1)加大样品和标准品的使用量至60微升，其余试剂用量不变。(2)把整个检测体系每种试剂的用量加大50%，这样可以使检测灵敏度增加约50%。如果上述方法还不能解决问题，可以考虑浓缩样品，即一方面在收集样品的时候尽量使一氧化氮的浓度保持得较高(例如裂解细胞时采用较小体积的裂解液)，另一方面可以考虑用真空干燥或真空冷冻干燥的方法浓缩样品。对于培养的细胞，通常上清液测定出来的吸光度相对较低，而细胞裂解液测定出来的吸光度会稍高一些。
2．检测时发现每个样品的吸光度都非常高。
在使用RPMI 1640培养液时会发生这种情况。因为RPMI 1640培养液中含有高浓度的硝酸盐从而会使样品检测出来的吸光度都非常高。其他含有高浓度硝酸盐的试剂也会产生类似情况，影响氧化还原反应的试剂也可能产生类似干扰。使用过程中避免使用RPMI 1640等可能导致干扰检测的试剂即可。

物质安全数据单

输入右侧验证码点击下载：

下载

质检证书

输入批号搜寻COA

搜索

相关产品请点击如下按钮：

一氧化氮相关

使用本产品的文献：

1. Dan Shi, TianShu Han, Xia Chu, Huimin Lu, Xue Yang, TianQi Zi, YanHe Zhao, XinYue Wang, ZhiPeng Liu, JingQi Ruan, Xin Liu, Hua Ning, MaoQing Wang, Zhen Tian, Wei Wei, Yue Sun, YinLing Li, Rui Guo, Yu Wang, Fan Ling, Yue Guan, Da Shen, YuCun Niu, Ying Li, ChangHao Sun

An isocaloric moderately high-fat diet extends lifespan in male rats and Drosophila

Cell Metab. 2021 Mar 2;33(3):581-597.e9. doi: 10.1016/j.cmet.2020.12.017. (IF 21.567)

2. Dashuai Zhu, Jingli Hou, Meng Qian, Dawei Jin, Tian Hao, Yanjun Pan, He Wang, Shuting Wu, Shuo Liu, Fei Wang, Lanping Wu, Yumin Zhong, Zhilu Yang, Yongzhe Che, Jie Shen, Deling Kong, Meng Yin, Qiang Zhao

Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery

Nat Commun. 2021 Jul 23;12(1):4501. doi: 10.1038/s41467-021-24804-3. (IF 12.121)

3. Jingwu Zhu, Jiang Tian, Chao Yang, Junpeng Chen, Lihuang Wu, Mengni Fan, Xiaojun Cai

L-Arg-Rich Amphiphilic Dendritic Peptide as a Versatile NO Donor for NO/Photodynamic Synergistic Treatment of Bacterial Infections and Promoting Wound Healing

Small. 2021 Aug;17(32):e2101495. doi: 10.1002/smll.202101495. (IF 11.459)

4. Lin Q, Ding X, Qiu F, Song X, Fu G, Ji J.

In situ endothelialization of intravascular stents coated with an anti-CD34 antibody functionalized heparin-collagen multilayer.

Biomaterials. 2010;31(14):4017-25. (IF 10.317)

5. Wenbin Dai, Yongyan Deng, Xiaohui Chen, Yue Huang, Haitao Hu, Qiao Jin, Zhe Tang, Jian Ji

A mitochondria-targeted supramolecular nanoplatform for peroxynitrite-potentiated oxidative therapy of orthotopic hepatoma

Biomaterials. 2022 Nov:290:121854. doi: 10.1016/j.biomaterials.2022.121854. (IF 10.317)

6. Jing Cao, Guogang Zhang, Zhaoya Liu, Qian Xu, Chan Li, Guangjie Cheng, Ruizheng Shi

Peroxidasin promotes diabetic vascular endothelial dysfunction induced by advanced glycation end products via NOX2/HOCl/Akt/eNOS pathway

Redox Biol. 2021 Sep;45:102031. doi: 10.1016/j.redox.2021.102031. (IF 9.986)

7. Liu L, Liu J, Wong WT, Tian XY, Lau CW, Wang YX, Xu G, Pu Y, Zhu Z, Xu A, Lam KS, Chen ZY, Ng CF, Yao X, Huang Y.

Dipeptidyl peptidase 4 inhibitor sitagliptin protects endothelial function in hypertension through a glucagon-like peptide 1-dependent mechanism.

Hypertension. 2012 Sep;60(3):833-41. (IF 7.713)

8. Junling Gao, Tong Lei, Hongyun Wang, Kai Luo, Yuanli Wang, Bingqing Cui, Zhuoran Yu, Xiaoqi Hu, Fang Zhang, Yingjie Chen, Wenjun Ding, Zhongbing Lu

Dimethylarginine dimethylaminohydrolase 1 protects PM2.5 exposure-induced lung injury in mice by repressing inflammation and oxidative stress

Part Fibre Toxicol. 2022 Oct 14;19(1):64. doi: 10.1186/s12989-022-00505-7. (IF 7.546)

9. Deng Z, Wang Z, Jin J, Wang Y, Bao N, Gao Q, Zhao J.

SIRT1 protects osteoblasts against particle-induced inflammatory responses and apoptosis in asepticprosthesis loosening.

Acta Biomater. 2017 Feb;49:541-554. (IF 7.242)

10. Deng Z, Wang Z, Jin J, Wang Y, Bao N, Gao Q, Zhao J.

SIRT1 protects osteoblasts against particle-induced inflammatory responses and apoptosis in aseptic prosthesis loosening.

Acta Biomater. 2017 Feb;49:541-554. (IF 7.242)

11. He XT, Wu RX, Xu XY, Wang J, Yin Y, Chen FM.

Macrophage involvement affects matrix stiffness-related influences on cell osteogenesis underthree-dimensional culture conditions.

Acta Biomater. 2018 Feb 17. pii: S1742-7061(18)30085-0. (IF 7.242)

12. He XT, Wu RX, Xu XY, Wang J, Yin Y, Chen FM

Macrophage involvement affects matrix stiffness-related influences on cell osteogenesis under three-dimensional culture conditions.

Acta Biomater. 2018 Apr 15;71:132-147. (IF 7.242)

13. Xue J, Yu C, Sheng W, Zhu W, Luo J, Zhang Q, Yang H, Cao H, Wang W, Zhou J, Wu J, Cao P, Chen M, Ding WQ, Cao J, Zhang S.

The Nrf2/GCH1/BH4 Axis Ameliorates Radiation-Induced Skin Injury by Modulating the ROSCascade.

J Invest Dermatol. 2017 Oct;137(10):2059-2068. (IF 7.143)

14. Hou L, Yang P, Jiang F, Liu Q, Wang X, Kang L.

The neuropeptide F/nitric oxide pathway is essential for shaping locomotor plasticity underlyinglocust phase transition.

Elife. 2017 Mar 27;6. pii: e22526. (IF 7.08)

15. Hui Li, Linlin Liu, Zhiwen Cao, Wen Li, Rui Liu, Youwen Chen, Chenxi Li, Yurong Song, Guangzhi Liu, Jinghong Hu, Zhenli Liu, Cheng Lu, Yuanyan Liu

Naringenin ameliorates homocysteine induced endothelial damage via the AMPKα/Sirt1 pathway

J Adv Res. 2021 Jan 23;34:137-147. doi: 10.1016/j.jare.2021.01.009. (IF 6.992)

16. Weiwei Wu, Yan Yang, Zhuoying Liang, Xiling Song, Yadong Huang, Lin Qiu, Xiaozhong Qiu, Siming Yu, Wei Xue

Near infrared II laser controlled free radical releasing nanogenerator for synergistic nitric oxide and alkyl radical therapy of breast cancer

Nanoscale. 2021 Jul 7;13(25):11169-11187. doi: 10.1039/d1nr01859k. (IF 6.895)

17. Li X, Li X, Shang Q, Gao Z, Hao F, Guo H, Guo C.

Fecal microbiota transplantation (FMT) could reverse the severity of experimental necrotizingenterocolitis (NEC) via oxidative stress modulation.

FREE RADICAL BIO MED. 2017 Jul;108:32-43. (IF 6.17)

18. Wang H, Shen X, Tian G, Shi X, Huang W, Wu Y, Sun L, Peng C, Liu S, Huang Y, Chen X, Zhang F, Chen Y, Ding W, Lu Z

AMPKα2 deficiency exacerbates long-term PM2.5 exposure-induced lung injury and cardiac dysfunction.

FREE RADICAL BIO MED. 2018 Jun;121:202-214. (IF 6.17)

19. Peng YL, Liu YN, Liu L, Wang X, Jiang CL, Wang YX.

Inducible nitric oxide synthase is involved in the modulation of depressive behaviors induced byunpredictable chronic mild stress.

J NEUROINFLAMM. 2012 Jul 6;9:75. (IF 5.793)

20. Wei J, Zhou T, Hu Z, Li Y, Yuan H, Zhao K, Zhang H, Liu C

Effects of triclocarban on oxidative stress and innate immune response in zebrafish embryos.

Chemosphere. 2018 Nov;210:93-101. (IF 5.778)

21. Chun-Yu Yin, Shu-Ying Huang, Ling Gao, Yu-Hui Lin, Lei Chang, Hai-Yin Wu, Dong-Ya Zhu, Chun-Xia Luo

Neuronal Nitric Oxide Synthase in Nucleus Accumbens Specifically Mediates Susceptibility to Social Defeat Stress through Cyclin-Dependent Kinase 5

J Neurosci. 2021 Mar 17;41(11):2523-2539. doi: 10.1523/JNEUROSCI.0422-20.2021. (IF 5.673)

22. Wang M, Zhao XR, Wang P, Li L, Dai Y, Huang H, Lei P, Zhu HF, Shen GX.

Glucose regulated proteins 78 protects insulinoma cells (NIT-1) from death induced by streptozotocin, cytokines or cytotoxic T lymphocytes.

INT J BIOCHEM CELL B. 2007;39(11):2076-82. (IF 3.673)

23. Zhong W, Zou G, Gu J, Zhang J.

L-arginine attenuates high glucose-accelerated senescence in human umbilical vein endothelial cells.

Diabetes Res Clin Pract. 2010;89(1):38-45.

24. Ling Y, Ye X, Ji H, Zhang Y, Lai Y, Peng S, Tian J.

Synthesis and evaluation of nitric oxide-releasing derivatives of farnesylthiosalicylic acid as anti-tumor agents.

BIOORG MED CHEM LETT. 2010 ;18(10):3448-56. (IF 2.572)

25. Zhang XP, Xiong JY, Jiao YX, Wang G, Zuo ZY.

Involvement of mitochondrial ATP-sensitive potassium channels in etomidate preconditioning-induced protection in human myeloid HL-60 cells.

Environmental Toxicology and Pharmacology. 2010;29:320–22. (IF 3.061)

26. Zou CG, Zhao YS, Gao SY, Li SD, Cao XZ, Zhang M, Zhang KQ.

Homocysteine promotes proliferation and activation of microglia.

Neurobiol Aging. 2010;31(12):2069-79. (IF 4.347)

27. Jin Y, Zheng S, Fu Z.

Embryonic exposure to cypermethrin induces apoptosis and immunotoxicity in zebrafish (Daniorerio).

FISH SHELLFISH IMMUN. 2011 Apr-May;30(4-5):1049-54. (IF 3.298)

28. Zhong X, Xiu LL, Wei GH, Liu YY, Su L, Cao XP, Li YB, Xiao HP.

Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK andeNOS activation.

Acta Pharmacol Sin. 2011 May;32(5):591-600. (IF 5.064)

29. Liu Y, He J, Jiang L, Wu H, Xiao Y, Liu Y, Li G, Du Y, Liu C, Wan J.

Nitric oxide production is associated with response to brown planthopper infestation in rice.

J Plant Physiol. 2011 May 15;168(8):739-45. (IF 3.013)

30. Zhang H, Li W, Wang G, Su Y, Zhang C, Chen X, Xu Y, Li K.

The distinct binding properties between avian/human influenza A virus NS1 and Postsynapticdensity protein-95 (PSD-95), and inhibition of nitric oxide production.

Virol J. 2011 Jun 13;8:298. (IF 2.579)

31. Fu R, Chen Z, Wang Q, Guo Q, Xu J, Wu X.

XJP-1,a novel ACEI, with anti-inflammatory properties in HUVECs.

Atherosclerosis. 2011 Nov;219(1):40-8. (IF 3.919)

32. Hu SQ, Ye JS, Zong YY, Sun CC, Liu DH, Wu YP, Song T, Zhang GY.

S-nitrosylation of mixed lineage kinase 3 contributes to its activation after cerebral ischemia.

J Biol Chem. 2012 Jan 20;287(4):2364-77. (IF 4.238)

33. Jia Y, Zhao Z, Xu M, Zhao T, Qiu Y, Ooi Y, Yang B, Rong R, Zhu T.

Prevention of renal ischemia-reperfusion injury by short hairpin RNA of endothelin A receptor in a rat model.

EXP BIOL MED. 2012 Aug 1;237(8):894-902. (IF 3.139)

34. Song H, Yin W, Zeng Q, Jia H, Lin L, Liu X, Mu L, Wang R.

Hemokinins modulate endothelium function and promote angiogenesis through neurokinin-1receptor.

INT J BIOCHEM CELL B. 2012 Sep;44(9):1410-21. (IF 3.673)

35. Zhang N, Gong L, Zhang H, Cao C.

High glucose-induced dysfunction of endothelial cells can be restored by HoxA9EC.

Ann Vasc Surg. 2012 Oct;26(7):1002-10. (IF 1.125)

36. Jiao K, Zhang J, Zhang M, Wei Y, Wu Y, Qiu ZY, He J, Cao Y, Hu J, Zhu H, Niu LN, Cao X, Yang K, Wang MQ.

The identification of CD163 expressing phagocytic chondrocytes in joint cartilage and its novel scavenger role incartilage degradation.

PLoS One. 2013;8(1):e53312. (IF 2.74)

37. Jiang Q, Zhou Z, Wang L, Shi X, Wang J, Yue F, Yi Q, Yang C, Song L.

The immunomodulation of inducible nitric oxide in scallop Chlamys farreri.

FISH SHELLFISH IMMUN. 2013 Jan;34(1):100-8. (IF 3.298)

38. Zhong XN, Wang HH, Lu ZQ, Dai YQ, Huang JH, Qiu W, Shu YQ, Xu W, Cheng C, Hu XQ.

Effects of Naoxintong on atherosclerosis and inducible nitric oxide synthase expression in atherosclerotic rabbit.

CHINESE MED J-PEKING. 2013 Mar;126(6):1166-70. (IF 1.585)

39. Jin LF, Wang YY, Zhang ZD, Yuan YM, Hu YR, Wei YF, Ni J.

Cytotoxicity and genome-wide microarray analysis of intestinal smooth muscle cells in response to hexavalent chromium induction.

动物学研究. 2013 Jun 8;34(3):E93-E100.

40. Song Y, Zhao XP, Song K, Shang ZJ.

Ephrin-A1 is up-regulated by hypoxia in cancer cells and promotes angiogenesis of HUVECs through a coordinated cross-talk with eNOS.

PLoS One. 2013 Sep 9;8(9):e74464. (IF 2.74)

41. Zhang J, Niu N, Li B, McNutt MA.

Neuron-derived IgG protects neurons from complement-dependent cytotoxicity.

J Histochem Cytochem. 2013 Dec;61(12):869-79. (IF 2.187)

42. Jiang XS, Ni YQ, Liu TJ, Zhang M, Jiang R, Xu GZ.

Generation and characterization of immortalized rat retinal microglial cell lines.

J Neurosci Res. 2014 Apr;92(4):424-31. (IF 4.699)

43. Wang T, Sun P, Chen L, Huang Q, Chen K, Jia Q, Li Y, Wang H.

Cinnamtannin D-1 protects pancreatic β-cells from palmitic acid-induced apoptosis by attenuating oxidative stress.

J AGR FOOD CHEM. 2014 Jun 4;62(22):5038-45. (IF 4.192)

44. Cao Q, Jiang Y, Shi J, Xu C, Liu X, Yang T, Fu P, Niu T.

Artemisinin inhibits the proliferation, migration, and inflammatory reaction induced by tumor necrosis factor-α in vascular smooth muscle cells through nuclear factor kappa B pathway.

J Surg Res. 2015 Apr;194(2):667-78. (IF 1.841)

45. Li YH, Xu Q, Xu WH, Guo XH, Zhang S, Chen YD.

Mechanisms of protection against diabetes-induced impairment of endothelium-dependent vasorelaxation by Tanshinone IIA.

BBA-BIOMEMBRANES. 2015 Apr;1850(4):813-23. (IF 3.411)

46. Yuan C, Zhang H, Wang W, Li Y, Yan R, Xu L, Song X, Li X.

Transmembrane protein 63A is a partner protein of Haemonchus contortus galectin in the regulation of goat peripheral blood mononuclear cells.

PARASITE VECTOR. 2015 Apr 9;8:211. (IF 2.824)

47. Zhao Q, Zhang J, Wang H.

PGC-1α overexpression suppresses blood pressure elevation in DOCA-salt hypertensive mice.

BIOSCIENCE REP. 2015 May 21;35(3). (IF 2.942)

48. Wang ZC, Liu H, Bai YG, Yu JW, Zhang HJ, Cheng YP, Bao JX, Ren XL, Ma HZ, Ma J.

28-Day hindlimb unweighting reduces expression of Rho kinase and inhibits its effects in femoral artery of rat.

J Physiol Biochem. 2015 Jun;71(2):205-16. (IF 2.952)

49. Liu XB, Yang BX, Zhang L, Lu YZ, Gong MH, Tian JK.

An in vivo and in vitro assessment of the anti-inflammatory, antinociceptive, and immunomodulatory activities of Clematis terniflora DC. extract, participation of aurantiamide acetate.

J Ethnopharmacol. 2015 Jul 1;169:287-94. (IF 3.69)

50. Zhao B, Zhou B, Bao L, Yang Y, Guo K.

Alpha-Tomatine Exhibits Anti-inflammatory Activity in Lipopolysaccharide-Activated Macrophages.

Inflammation. 2015 Oct;38(5):1769-76. (IF 3.212)

51. Tian X, Zhao L, Song X, Yan Y, Liu N, Li T, Yan B, Liu B.

HSP27 Inhibits Homocysteine-Induced Endothelial Apoptosis by Modulation of ROS Production andMitochondrial Caspase-Dependent Apoptotic Pathway.

Biomed Res Int. 2016;2016:4847874. (IF 2.276)

52. Yao J, Zou Z, Wang X, Ji X, Yang J.

Pinoresinol Diglucoside Alleviates oxLDL-Induced Dysfunction in Human Umbilical Vein Endothelial Cells.

EVID-BASED COMPL ALT. 2016;2016:3124519. (IF 1.813)

53. Zhang ZB, Ruan CC, Chen DR, Zhang K, Yan C, Gao PJ.

Activating transcription factor 3 SUMOylation is involved in angiotensin II-induced endothelial cellinflammation and dysfunction.

J Mol Cell Cardiol. 2016 Mar;92:149-57. (IF 4.133)

54. Li P, Zhang L, Zhang M, Zhou C, Lin N.

Uric acid enhances PKC-dependent eNOS phosphorylation and mediates cellular ER stress: A mechanismfor uric acid-induced endothelial dysfunction.

Int J Mol Med. 2016 Apr;37(4):989-97. (IF 3.098)

55. Liu J, Zhang W, Shi H, Yang K, Wang G, Wang P, Ji J, Chu PK.

In situ plasma fabrication of ceramic-like structure on polymeric implant with enhanced surface hardness,cytocompatibility and antibacterial capability.

J Biomed Mater Res A. 2016 May;104(5):1102-12. (IF 3.525)

56. Gadahi JA, Yongqian B, Ehsan M, Zhang ZC, Wang S, Yan RF, Song XK, Xu LX, Li XR.

Haemonchus contortus excretory and secretory proteins (HcESPs) suppress functions of goat PBMCs invitro.

ONCOTARGET. 2016 Jun 14;7(24):35670-35679. (IF 5.168)

57. Li Y, Yuan C, Wang L, Lu M, Wang Y, Wen Y, Yan R, Xu L, Song X, Li X.

Transmembrane protein 147 (TMEM147): another partner protein of Haemonchus

PARASITE VECTOR. 2016 Jun 23;9(1):355. (IF 2.824)

58. Zhou G, Shi QS, Huang XM, Xie XB.

Comparison of transcriptomes of wild-type and isothiazolone-resistant Pseudomonas aeruginosa by usingRNA-seq.

Mol Biol Rep. 2016 Jun;43(6):527-40. (IF 1.402)

59. Lu J, Kan S, Zhao Y, Zhang W, Liu J.

Novel naproxen/esomeprazole magnesium compound pellets based on acid-independent mechanism: invitro and in vivo evaluation.

Drug Dev Ind Pharm. 2016 Sep;42(9):1495-503. (IF 2.365)

60. Linghu K, Lin D, Yang H, Xu Y, Zhang Y, Tao L, Chen Y, Shen X.

Ameliorating effects of ,8-cineole on LPS-induced human umbilical vein endothelial cell injury bysuppressing NF-κB signaling in vitro.

Eur J Pharmacol. 2016 Oct 15;789:195-201. (IF 3.263)

61. Ren Y, Tao S, Zheng S, Zhao M, Zhu Y, Yang J, Wu Y.

Salvianolic acid B improves vascular endothelial function in diabetic rats with blood glucose fluctuations viasuppression of endothelial cell apoptosis.

Eur J Pharmacol. 2016 Nov 15;791:308-315. (IF 3.263)

62. Gao Y, Wang W, Cao J, Wang F, Geng Y, Cao J, Xu X, Zhou J, Liu P, Zhang S.

Upregulation of AUF1 is involved in the proliferation of esophageal squamous

Int J Oncol. 2016 Nov;49(5):2001-2010. (IF 3.899)

63. Sun X, Jiao X, Ma Y, Liu Y, Zhang L, He Y, Chen Y.

Trimethylamine N-oxide induces inflammation and endothelial dysfunction in human umbilical veinendothelial cells via activating ROS-TXNIP-NLRP3 inflammasome.

BIOCHEM BIOPH RES CO. 2016 Dec 2;481(1-2):63-70. (IF 2.985)

64. Gadahi JA, Li B, Ehsan M, Wang S, Zhang Z, Wang Y, Hasan MW, Yan R, Song X, Xu L, Li X.

Recombinant Haemonchus contortus 24 kDa excretory/secretory protein (rHcES-24) modulate the immunefunctions of goat PBMCs in vitro.

ONCOTARGET. 2016 Dec 20;7(51):83926-83937. (IF 5.168)

65. Gadahi JA, Ehsan M, Wang S, Zhang Z, Wang Y, Yan R, Song X, Xu L, Li X.

Recombinant protein of Haemonchus contortus 14-3-3 isoform 2 (rHcftt-2) decreased the production of IL-4and suppressed the proliferation of goat PBMCs in vitro.

Exp Parasitol. 2016 Dec;171:57-66. (IF 1.69)

66. Li J, Geng XY, Cong XL.

Corrigendum to "PGC-1α ameliorates AngiotensinII-induced eNOS dysfunction in human

VASC PHARMACOL. 2016 Dec;87:248. (IF 4.152)

67. Yan Y, Du Y, Zheng H, Wang G, Li R, Chen J, Li K.

NS1 of H7N9 Influenza A Virus Induces NO-Mediated Cellular Senescence in Neuro2a Cells.

CELL PHYSIOL BIOCHEM. 2017;43(4):1369-1380. (IF 5.5)

68. Wang Z, Lv Q, Liu H, Wu Y, Bai Y, Cheng Y, Su Y, Cai Y, Yu J, Ma J, Bao J.

Caveolae Depletion Contributes to Vasorelaxant Effects of Chenodeoxycholic Acid.

CELL PHYSIOL BIOCHEM. 2017;42(3):1013-1024. (IF 5.5)

69. Guo Q, Xu L, Li H, Sun H, Liu J, Wu S, Zhou B.

Progranulin causes adipose insulin resistance via increased autophagy resulting from activated oxidativestress and endoplasmic reticulum stress.

Lipids Health Dis. 2017 Jan 31;16(1):25. (IF 2.906)

70. Wei SJ, Cheng L, Liang ES, Wang Q, Zhou SN, Xu H, Hui LH, Ge ZM, Zhang MX.

Poly(ADP-ribose) polymerase 1 deficiency increases nitric oxide production and attenuates aorticatherogenesis through downregulation of arginase II.

CLIN EXP PHARMACOL P . 2017 Jan;44(1):114-122. (IF 2.092)

71. Liu C, Hao Y, Huang J, Li H, Yang Z, Zeng Y, Liu J, Li R.

Ghrelin accelerates wound healing in combined radiation and wound injury in mice.

Exp Dermatol. 2017 Feb;26(2):186-193. (IF 3.368)

72. Guo J, Wang Y, Wang J, Zhang J, Fang J.

Radiosensitization of oral tongue squamous cell carcinoma by nanosecond pulsed electric fields (nsPEFs).

Bioelectrochemistry. 2017 Feb;113:35-41. (IF 4.722)

73. Huang Q, Wang T, Wang HY.

Ginsenoside Rb2 enhances the anti-inflammatory effect ofω-3 fatty acid in LPS-stimulatedRAW264.7 macrophages by upregulating GPR120 expression.

Acta Pharmacol Sin. 2017 Feb;38(2):192-200. (IF 5.064)

74. Li XH, Xue WL, Wang MJ, Zhou Y, Zhang CC, Sun C, Zhu L, Liang K, Chen Y, Tao BB, Tan B, Yu B, Zhu YC.

H2S regulates endothelial nitric oxide synthase protein stability by promoting microRNA-455-3pexpression.

SCI REP-UK. 2017 Mar 21;7:44807. (IF 3.998)

75. Chen XH, Liu SR, Peng B, Li D, Cheng ZX, Zhu JX, Zhang S, Peng YM, Li H, Zhang TT, Peng XX.

Exogenous l-Valine Promotes Phagocytosis to Kill Multidrug-Resistant Bacterial Pathogens.

Front Immunol. 2017 Mar 6;8:207. (IF 5.085)

76. Ehsan M, Gao W, Gadahi JA, Lu M, Liu X, Wang Y, Yan R, Xu L, Song X, Li X.

Arginine kinase from Haemonchus contortus decreased the proliferation and increased the apoptosis of goat PBMCs in vitro.

PARASITE VECTOR. 2017 Jun 26;10(1):311. (IF 2.824)

77. Qing L, Ariyadewa DK, Yi H, Wang Y, Zhou Q, Xu W.

Skin Lesions in Swine with Decompression Sickness: Clinical Appearance and Pathogenesis.

Front Physiol. 2017 Jul 25;8:540. (IF 3.367)

78. Liu X, Ma Q, Sun X, Lu M, Ehsan M, Hasan MW, Xu L, Yan R, Song X, Li X.

Effects of Recombinant Toxoplasma gondii Citrate Synthase Ionthe Cellular Functions of MurineMacrophages In vitro.

Front Microbiol. 2017 Jul 21;8:1376. (IF 4.235)

79. Chen P, Gao H, Lu Y, Nie H, Liu Z, Zhao Y, Fan N, Zou Q, Dai Y, Tang A, Hara H, Cai Z, Cooper DKC, Lai L, Mou L.

Altered expression of eNOS, prostacyclin synthase, prostaglandin G/H synthase,and thromboxane synthase in porcine aortic endothelial cells after exposure to human serum-relevance to xenotransplantation.

Cell Biol Int. 2017 Jul;41(7):798-808. (IF 2.571)

80. Jiang J, Gan Z, Li Y, Zhao W, Li H, Zheng JP, Ke Y.

REM sleep deprivation induces endothelial dysfunction and hypertension in middle-aged rats: Roles ofthe eNOS/NO/cGMP pathway and supplementation with L-arginine.

PLoS One. 2017 Aug 15;12(8):e0182746. (IF 2.74)

81. Hou N, Jiang N, Zou Y, Piao X, Liu S, Li S, Chen Q.

Down-Regulation of Tim-3 in Monocytes and Macrophages in Plasmodium Infection and Its Association with Parasite Clearance.

Front Microbiol. 2017 Aug 2;8:1431. (IF 4.235)

82. Lu M, Tian X, Yang X, Yuan C, Ehsan M, Liu X, Yan R, Xu L, Song X, Li X.

TheN-and C-terminal carbohydrate recognition domains of Haemonchus contortus galectin bind to distinct receptors of goat PBMC and contribute differently to its immunomodulatory functions in host-parasite interactions.

PARASITE VECTOR. 2017 Sep 5;10(1):409. (IF 2.824)

83. Shang Q, Bao L, Guo H, Hao F, Luo Q, Chen J, Guo C.

Contribution of glutaredoxin-1 to S-glutathionylation of endothelial nitric oxide synthase for mesenteric nitric oxide generation in experimental necrotizing enterocolitis.

Transl Res. 2017 Oct;188:92-105. (IF 5.411)

84. Long Y, Huang C, Wu J, Cheng JN, Liang GN, Jiang CX, Wan Q.

2,3',4,4',5-Pentachlorobiphenyl impairs insulin-induced NO production partly through excessiveROS production in endothelial cells.

TOXICOL MECH METHOD. 2017 Oct;27(8):592-597. (IF 2.295)

85. Gadahi JA, Ehsan M, Wang S, Zhang Z, Yan R, Song X, Xu L, Li X.

Recombinant protein of Haemonchus contortus small GTPase ADP-ribosylation factor 1 (HcARF1) modulate the cell mediated immune response in vitro.

ONCOTARGET. 2017 Nov 26;8(68):112211-21. (IF 5.168)

86. Qiu Y, Sui X, Cao S, Li X, Ning Y, Wang S, Yin L, Zhi X.

Steroidogenic Acute Regulatory Protein (StAR) Overexpression Reduces Inflammation and Insulin Resistance in Obese Mice.

J Cell Biochem. 2017 Nov;118(11):3932-3942. (IF 4.237)

87. Zheng Y, Wu Z, Yi F, Orange M, Yao M, Yang B, Liu J, Zhu H

By Activating Akt/eNOS Bilobalide B Inhibits Autophagy and Promotes Angiogenesis Following Focal Cerebral Ischemia Reperfusion.

CELL PHYSIOL BIOCHEM. 2018;47(2):604-616. (IF 5.5)

88. Li H, Chen LP, Wang T, Wang SG, Liu JH.

Calpain inhibition improves erectile function in diabetic mice via upregulating endothelial nitricoxide synthase expression and reducing apoptosis.

Asian J Androl. 2018 Jan 9. (IF 2.448)

89. Zhu BB, Wang H, Chi YF, Wang YM, Yao XM, Liu S, Qiu H, Fang J, Yin PH, Zhang XM, Peng W.

Protective effects of probucol on Ox-LDL-induced epithelial-mesenchymal transition in human renal proximal tubular epithelial cells via LOX 1/ROS/MAPK signaling.

Mol Med Rep. 2018 Jan;17(1):1289-1296. (IF 2.1)

90. Mao J, Hu X, Pang P, Zhou B, Zhang Y, Li D, Shan H.

Establishment ofa CRISPR/Cas9-Mediated Cysltr1 Knockout Mouse Model and iTRAQ-BasedProteomic Analysis.

PROTEOM CLIN APPL. 2018 Jan 26. (IF 2.489)

91. He SW, Wang GH, Yue B, Zhou S, Zhang M.

TO17:A teleost antimicrobial peptide that induces degradation of bacterial nucleic acids and inhibits bacterial infection in red drum, Sciaenops ocellatus.

FISH SHELLFISH IMMUN. 2018 Jan;72:639-645. (IF 3.298)

92. Ma LL, Li Y, Yin PP, Kong FJ, Guo JJ, Shi HT, Zhu JB, Zou YZ, Ge JB.

Hypertrophied myocardium is vulnerable to ischemia/reperfusion injury and refractory to rapamycin-induced protection dueto increased oxidative/nitrative stress.

CLIN SCI. 2018 Jan 11;132(1):93-110. (IF 5.223)

93. Zhang B, Zhang Z, Ji H, Shi H, Chen S, Yan D, Jiang X, Shi B

Grape seed proanthocyanidin extract alleviates urethral dysfunction in diabetic rats through modulating the NO-cGMP pathway.

Exp Ther Med. 2018 Jan;15(1):1053-1061. (IF 1.785)

94. He SW, Wang GH, Yue B, Zhou S, Zhang M

TO17: A teleost antimicrobial peptide that induces degradation of bacterial nucleic acids and inhibits bacterial infection in red drum, Sciaenops ocellatus.

FISH SHELLFISH IMMUN. 2018 Jan;72:639-645. (IF 3.298)

95. Deng X, Huang W, Peng J, Zhu TT, Sun XL, Zhou XY, Yang H, Xiong JF, He HQ, Xu YH, He YZ.

Irisin Alleviates Advanced Glycation End Products-Induced Inflammation and EndothelialDysfunction via Inhibiting ROS-NLRP3 Inflammasome Signaling.

Inflammation. 2018 Feb;41(1):260-275. (IF 3.212)

96. Long Y, Chen SW, Gao CL, He XM, Liang GN, Wu J, Jiang CX, Liu X, Wang F, Chen F.

ATP2B1 GeneSilencing Increases NO Production Under Basal Conditions ThroughtheCa2+/calmodulin/eNOS Signaling Pathway in Endothelial Cells.

Hypertens Res. 2018 Feb 7. (IF 2.941)

97. Deng X, Huang W, Peng J, Zhu TT, Sun XL, Zhou XY, Yang H, Xiong JF, He HQ, Xu YH, He YZ

Irisin Alleviates Advanced Glycation End Products-Induced Inflammation and Endothelial Dysfunction via Inhibiting ROS-NLRP3 Inflammasome Signaling.

Inflammation. 2018 Feb;41(1):260-275. (IF 3.212)

98. Ma LL, Ma X, Kong FJ, Guo JJ, Shi HT, Zhu JB, Zou YZ, Ge JB.

Mammaliantargetofrapamycin inhibition attenuates myocardial ischaemia-reperfusion injury in hypertrophic heart.

J Cell Mol Med. 2018 Mar;22(3):1708-1719. (IF 4.486)

99. Pan P, Zhang H, Su L, Wang X, Liu D

Melatonin Balance the Autophagy and Apoptosis by Regulating UCP2 in the LPS-Induced Cardiomyopathy.

Molecules. 2018 Mar 16;23(3). pii: E675. (IF 3.267)

100. Tian AL, Lu M, Calderón-Mantilla G, Petsalaki E, Dottorini T, Tian X, Wang Y, Huang SY, Hou JL, Li X, Elsheikha HM, Zhu XQ

A recombinant Fasciola gigantica 14-3-3 epsilon protein (rFg14-3-3e) modulates various functions of goat peripheral blood mononuclear cells.

PARASITE VECTOR. 2018 Mar 6;11(1):152. (IF 2.824)

101. Cui K, Tang Z, Li CC, Wang T, Rao K, Wang SG, Liu JH, Chen Z

Lipoxin A4 improves erectile dysfunction in rats with type I diabetes by inhibiting oxidative stress and corporal fibrosis.

Asian J Androl. 2018 Mar-Apr;20(2):166-172. (IF 2.448)

102. Ma LL, Ma X, Kong FJ, Guo JJ, Shi HT, Zhu JB, Zou YZ, Ge JB.

Mammalian target of rapamycin inhibition attenuates myocardial ischaemia-reperfusion injury in hypertrophic heart.

J Cell Mol Med. 2018 Mar 22(3):1708-1719. (IF 4.486)

103. Zheng D, Cai A, Xu R, Mai Z, Zhou Y, Zeng F, Li L, Mai W

Effects and potential mechanism of atorvastatin treatment on Lp-PLA2 in rats with dyslipidemia.

Arch Med Sci. 2018 Apr;14(3):629-634. (IF 2.807)

104. Xu C, Shi Q, Zhang L, Zhao H

High molecular weight hyaluronan attenuates fine particulate matter-induced acute lung injury through inhibition of ROS-ASK1-p38/JNK-mediated epithelial apoptosis.

ENVIRON TOXICOL CHEM. 2018 Apr;59:190-198. (IF 3.152)

105. Long Y, Chen SW, Gao CL, He XM, Liang GN, Wu J, Jiang CX, Liu X, Wang F, Chen F

ATP2B1 Gene Silencing Increases NO Production Under Basal Conditions Through the Ca2+/calmodulin/eNOS Signaling Pathway in Endothelial Cells.

Hypertens Res. 2018 Apr;41(4):246-252. (IF 2.941)

106. Peng Y, Hu K

Effect of garlic on rats with chronic intermittent hypoxia combined with diabetes mellitus.

Mol Med Rep. 2018 Apr;17(4):6174-6184. (IF 2.1)

107. Liu S, Zhang C, Chao N, Lu J, Zhang Y

Cloning, Characterization, and Functional Investigation of VaHAESA from Vitis amurensis Inoculated with Plasmopara viticola.

Int J Mol Sci. 2018 Apr 16;19(4). pii: E1204. (IF 4.556)

108. Mao J, Hu X, Pang P, Zhou B, Zhang Y, Li D, Shan H

Establishment of a CRISPR/Cas9-Mediated Cysltr1 Knockout Mouse Model and iTRAQ-Based Proteomic Analysis.

PROTEOM CLIN APPL. 2018 May;12(3):e1700087. (IF 2.489)

109. Zhang Y, Dong F, Liu Z, Guo J, Zhang J, Fang J

Nanosecond pulsed electric fields promoting the proliferation of porcine iliac endothelial cells: An in vitro study.

PLoS One. 2018 May 1;13(5):e0196688. (IF 2.74)

110. Ehsan M, Wang W, Gadahi JA, Hasan MW, Lu M, Wang Y, Liu X, Haseeb M, Yan R, Xu L, Song X, Li X

The Serine/Threonine-Protein Phosphatase 1 From Haemonchus contortus Is Actively Involved in Suppressive Regulatory Roles on Immune Functions of Goat Peripheral Blood Mononuclear Cells.

Front Immunol. 2018 Jul 16;9:1627. (IF 5.085)

111. Luo W, Wang Y, Yang H, Dai C, Hong H, Li J, Liu Z, Guo Z, Chen X, He P, Li Z, Li F, Jiang J, Liu P, Li Z

Heme oxygenase-1 ameliorates oxidative stress-induced endothelial senescence via regulating endothelial nitric oxide synthase activation and coupling.

AGING-US. 2018 Jul 24;10(7):1722-1744. (IF 4.831)

112. Li H, Chen LP, Wang T, Wang SG, Liu JH

Calpain inhibition improves erectile function in diabetic mice via upregulating endothelial nitric oxide synthase expression and reducing apoptosis.

Asian J Androl. 2018 Jul-Aug;20(4):342-348. (IF 2.448)

113. Ma Y, Tang T, Sheng L, Wang Z, Tao H, Zhang Q, Zhang Y, Qi Z

Aloin suppresses lipopolysaccharide‑induced inflammation by inhibiting JAK1‑STAT1/3 activation and ROS production in RAW264.7 cells.

Int J Mol Med. 2018 Oct;42(4):1925-1934. (IF 3.098)

114. Zhang R, Ji J, Blaženović I, Pi F, Wang T, Zhang Y, Sun X

Investigation into Cellular Glycolysis for the Mechanism Study of Energy Metabolism Disorder Triggered by Lipopolysaccharide.

TOXINS. 2018 Oct 29;10(11). pii: E441. (IF 3.531)

115. Zhang F, Zhang JG, Yang W, Xu P, Xiao YL, Zhang HT

6-Gingerol attenuates LPS-induced neuroinflammation and cognitive impairment partially via suppressing astrocyte overactivation.

Biomed Pharmacother. 2018 Nov;107:1523-1529. (IF 4.545)

116. Luo J, Wei D, Li D, Wang L

Nitric oxide functions in stromal cell-derived factor-1-induced cytoskeleton changes and the migration of Jurkat cells.

Oncol Lett. 2018 Nov;16(5):6685-6690. (IF 2.311)

117. Zhao Z, Zhang H, Wang M, Zhang C, Kuang P, Zhou Z, Zhang G, Wang Z, Zhang B, Shi X

The ethanol extract of honeysuckle stem modulates the innate immunity of Chinese mitten crab Eriocheir sinensis against Aeromonas hydrophila.

FISH SHELLFISH IMMUN. 2018 Nov;82:304-311. (IF 3.298)

118. Liu X, Li X, Wang Q, Sun X, Lu M, Ehsan M, Xu L, Yan R, Song X, Li X

Toxoplasma gondii Histone 4 Affects Some Functions of Murine Ana-1 Macrophages In Vitro.

J Eukaryot Microbiol. 2018 Nov;65(6):860-869. (IF 2.143)

119. Tian AL, Lu M, Zhang FK, Calderón-Mantilla G, Petsalaki E, Tian X, Wang W, Huang SY, Li X, Elsheikha HM, Zhu XQ

The pervasive effects of recombinant Fasciola gigantica Ras-related protein Rab10 on the functions of goat peripheral blood mononuclear cells.

PARASITE VECTOR. 2018 Nov 6;11(1):579. (IF 2.824)

120. Song S, Wu S, Wang Y, Wang Z, Ye C, Song R, Song D, Ruan Y

17β-estradiol inhibits human umbilical vascular endothelial cell senescence by regulating autophagy via p53.

Exp Gerontol. 2018 Dec;114:57-66. (IF 3.376)

121. Yang B, Guo J, Xiao C.

Effect of PM2.5 environmental pollution on rat lung.

ENVIRON SCI POLLUT R. 2018 Dec 25(36):36136-36146. (IF 3.056)

122. Liu W, Xiang Y, Zhang X, Han G, Sun X, Sheng Y, Yan J, Scheller HV, Zhang A

Over-Expression of a Maize N-Acetylglutamate Kinase Gene (ZmNAGK) Improves Drought Tolerance in Tobacco.

Front Plant Sci. 2019 Jan 4;9:1902. (IF 4.402)

123. Deng Y, Cai Y, Liu L, Lin X, Lu P, Guo Y, Han M, Xu G

Blocking Tyr265 nitration of protein phosphatase 2A attenuates nitrosative stress-induced endothelial dysfunction in renal microvessels.

FASEB J. 2019 Mar;33(3):3718-3730. (IF 4.966)

124. Tu X, Qi X, Huang A, Ling F, Wang G

Cytokine gene expression profiles in goldfish (Carassius auratus) during Gyrodactylus kobayashii infection.

FISH SHELLFISH IMMUN. 2019 Mar 86:116-124. (IF 3.298)

125. Zhu B, Li Y, Mei W, He M, Ding Y, Meng B, Zhao H, Xiang G

Alogliptin improves endothelial function by promoting autophagy in perivascular adipose tissue of obese mice through a GLP-1-dependent mechanism.

VASC PHARMACOL. 2019 Apr;115:55-63. (IF 4.152)

126. Li M, Wang M, Wang W, Wang L, Liu Z, Sun J, Wang K, Song L

The immunomodulatory function of invertebrate specific neuropeptide FMRFamide in oyster Crassostrea gigas.

FISH SHELLFISH IMMUN. 2019 May 88:480-488. (IF 3.298)

127. Yan D, Zhang D, Lu L, Qiu H, Wang J

Vascular endothelial growth factor-modified macrophages accelerate reendothelialization and attenuate neointima formation after arterial injury in atherosclerosis-prone mice.

J Cell Biochem. 2019 Jun 120(6):10652-10661. (IF 4.237)

128. Wang Z, Song P, Li Y, Wang S, Fan J, Zhang X, Luan J, Chen W, Wang Y, Liu P, Ju D

Recombinant human arginase I elicited immunosuppression in activated macrophages through inhibiting autophagy.

APPL MICROBIOL BIOT. 2019 Jun 103(12):4825-4838. (IF 3.53)

129. Chang L, Wang Z, Ma F, Tran B, Zhong R, Xiong Y, Dai T, Wu J, Xin X, Guo W, Xie Y, Mao Y, Zhu YZ

ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway.

Oxid Med Cell Longev. 2019 Jun 2 2019:6173685. (IF 5.076)

130. Hao H, Tian W, Pan C, Jiao Y, Deng X, Fan J, Han J, Han S, Wang M, Li P

Marsdenia tenacissima extract dilated small mesenteric arteries via stimulating endothelial nitric oxide synthase and inhibiting calcium influx.

J Ethnopharmacol. 2019 Jun 28 238:111847. (IF 3.69)

131. Yan L, Yang J, Yu M, Lu Y, Huang L, Wang J, Lu X, Jin C, Wu S, Cai Y

Lanthanum chloride induces neuron damage by activating the nuclear factor-kappa B signaling pathway in activated microglia.

Metallomics. 2019 Jul 17 11(7):1277-1287. (IF 3.796)

132. Chen D, Tian AL, Hou JL, Li JX, Tian X, Yuan XD, Li X, Elsheikha HM, Zhu XQ

The Multitasking Fasciola gigantica Cathepsin B Interferes With Various Functions of Goat Peripheral Blood Mononuclear Cells in vitro.

Front Immunol. 2019 Jul 23 10:1707. (IF 5.085)

133. Lu Y, Gao X, Wang R, Sun J, Guo B, Wei R, Jia Y

Adiponectin inhibits proliferation of vascular endothelial cells induced by Ox-LDL by promoting dephosphorylation of Caveolin-1 and depolymerization of eNOS and up-regulating release of NO.

Int Immunopharmacol. 2019 Aug 73:424-434. (IF 3.943)

134. Liu C, Wu QQ, Cai ZL, Xie SY, Duan MX, Xie QW, Yuan Y, Deng W, Tang QZ

Zingerone attenuates aortic banding-induced cardiac remodelling via activating the eNOS/Nrf2 pathway.

J Cell Mol Med. 2019 Sep 23(9):6466-6478. (IF 4.486)

135. Zhang J, Zhang SD, Wang P, Guo N, Wang W, Yao LP, Yang Q, Efferth T, Jiao J, Fu YJ

Pinolenic acid ameliorates oleic acid-induced lipogenesis and oxidative stress via AMPK/SIRT1 signaling pathway in HepG2 cells.

Eur J Pharmacol. 2019 Oct 15 861:172618. (IF 3.263)

136. Liu Y, Ye X, Li Y, Chu Q, Yu L, Chen W, Jia R, Jiang Y, Zheng X

The influence of the extraction method on bioactivity of the root of Tetrastigma hemsleyanum.

Food Sci Nutr. 2019 Oct 21 7(11):3644-3653. (IF 1.797)

137. Deng CK, Mu ZH, Miao YH, Liu YD, Zhou L, Huang YJ, Zhang F, Wang YY, Yang ZH, Qian ZY, Wang X, Guo JZ, Zhang MY, Liao XY, Wan Q, Lu D, Zou YY

Gastrodin Ameliorates Motor Learning Deficits Through Preserving Cerebellar Long-Term Depression Pathways in Diabetic Rats.

FRONT NEUROSCI-SWITZ. 2019 Nov 22 13:1239. (IF 3.707)

138. Wang X, Chen S, Ren H, Chen J, Li J, Wang Y, Hua Y, Wang X, Huang N

HMGN2 regulates non-tuberculous mycobacteria survival via modulation of M1 macrophage polarization.

J Cell Mol Med. 2019 Dec 23(12):7985-7998. (IF 4.486)

139. Shi Q, Zhao L, Zhang L

Astragalus polysaccharide strengthens the inflammatory and immune responses of Brucella suis S2-infected mice and macrophages.

Exp Ther Med. 2019 Dec 18(6):4295-4302. (IF 1.785)

140. Yang RH, Tan X, Ge LJ, Sun JC, Peng XD, Wang WZ

Interleukin enhancement binding factor 3 inhibits cardiac hypertrophy by targeting asymmetric dimethylarginine-nitric oxide.

NITRIC OXIDE-BIOL CH. 2019 Dec 1 93:44-52. (IF 3.311)

141. Qing Zhou, Qi Run, Chen-Yu Li, Xiang-Yu Xiong, Xiao-Lin Wu

LncRNA MALAT1 Promotes STAT3-Mediated Endothelial Inflammation by Counteracting the Function of miR-590

Cytogenet Genome Res. 2020;160(10):565-578. doi: 10.1159/000509811. (IF 1.114)

142. Xiuxiang Liu, Jinjin Wu, Chenying Zhu, Jie Liu, Xiaoli Chen, Tao Zhuang, Yashu Kuang, Yanfang Wang, Hao Hu, Ping Yu, Huimin Fan, Yuzhen Zhang, Zhongmin Liu, Lin Zhang

Endothelial S1pr1 regulates pressure overload-induced cardiac remodelling through AKT-eNOS pathway

J Cell Mol Med. 2020 Jan;24(2):2013-2026. doi: 10.1111/jcmm.14900. (IF 4.486)

143. Pan Huang, Xuefei Shao, Miaomiao Zhu, Baocai Xu, Conggui Chen, Peijun Li

Sucrose enhances colour formation in dry sausages by up-regulating gene expression of nitric oxide synthase in Staphylococcus vitulinus

Int J Food Microbiol. 2020 Feb 16;315:108419. doi: 10.1016/j.ijfoodmicro.2019.108419. (IF 4.187)

144. Zheng Y, Liu Z, Wang L, Li M, Zhang Y, Zong Y, Li Y, Song L

A novel tumor necrosis factor in the Pacific oyster Crassostrea gigas mediates the antibacterial response by triggering the synthesis of lysozyme and nitric oxide.

FISH SHELLFISH IMMUN. 2020 Mar 98:334-341. (IF 3.298)

145. Lu H, Sun L, Chen W, Zhou Y, Liu K, Chen J, Zhang Z, Zhang C, Tian H

Sirtuin 3 Therapy Attenuates Aging Expression, Oxidative Stress Parameters, and Neointimal Hyperplasia Formation in Vein Grafts.

Ann Vasc Surg. 2020 Apr 64:303-317. (IF 1.125)

146. Yujie Wei, Dongdong Lin, Zhanning Xu, Xiaoman Gao, Chaoshu Zeng, Haihui Ye

A Possible Role of Crustacean Cardioactive Peptide in Regulating Immune Response in Hepatopancreas of Mud Crab

Front Immunol. 2020 Apr 30;11:711. doi: 10.3389/fimmu.2020.00711. (IF 5.085)

147. Pengwei Luan, Jiazhen Xu, Xinyue Ding, Qianfei Cui, Lixian Jiang, Yulan Xu, Yuying Zhu, Ruixiang Li, Guoqiang Lin, Ping Tian, Jiange Zhang

Neuroprotective effect of salvianolate on cerebral ischaemia-reperfusion injury in rats by inhibiting the Caspase-3 signal pathway

Eur J Pharmacol. 2020 Apr 5;872:172944. doi: 10.1016/j.ejphar.2020.172944. (IF 3.263)

148. Jiaming Wang, Zhou Zhou, Dongmei Dan, Guoyuan Hu

Physicochemical properties and bioactivities of Lentinula edodes polysaccharides at different development stages

Int J Biol Macromol. 2020 May 1;150:573-577. doi: 10.1016/j.ijbiomac.2020.02.099. (IF 5.162)

149. Ping Gan, Lidong Ding, Guihua Hang, Qiaofang Xia, Zhimei Huang, Xing Ye, Xiaojuan Qian

Oxymatrine Attenuates Dopaminergic Neuronal Damage and Microglia-Mediated Neuroinflammation Through Cathepsin D-Dependent HMGB1/TLR4/NF-κB Pathway in Parkinson's Disease

Front Pharmacol. 2020 May 26;11:776. doi: 10.3389/fphar.2020.00776. (IF 4.225)

150. Yan Dai, Jun Zhang, Rong Liu, Na Xu, Song-Biao Yan, Yi Chen, Tian-He Li

The role and mechanism of asymmetric dimethylarginine in fetal growth restriction via interference with endothelial function and angiogenesis

J Assist Reprod Genet. 2020 May;37(5):1083-1095. doi: 10.1007/s10815-020-01750-5.

151. Qingbo Lv, Yao Wang, Ya Li, Liding Zhao, Yingchao Gong, Meihui Wang, Min Wang, Guosheng Fu, Wenbin Zhang

Rosuvastatin Reverses Hypertension-Induced Changes in the Aorta Structure and Endothelium-Dependent Relaxation in Rats Through Suppression of Apoptosis and Inflammation

J Cardiovasc Pharmacol. 2020 Jun;75(6):584-595. doi: 10.1097/FJC.0000000000000828.

152. Tao Yan, Tian Zhang, Wei Mu, Yuhong Qi, Shun Guo, Na Hu, Weihe Zhao, Song Zhang, Qinhui Wang, Lei Shi, Linna Liu

Ionizing radiation induces BH 4 deficiency by downregulating GTP-cyclohydrolase 1, a novel target for preventing and treating radiation enteritis

Biochem Pharmacol. 2020 Oct;180:114102. doi: 10.1016/j.bcp.2020.114102. (IF 4.96)

153. Feng Zhou, Zhizhen Liu, Huazhong Cai, Zhenjun Miao, Faxing Wei, Chao Song

Role of microRNA-15a-5p/TNFAIP3-interacting protein 2 axis in acute lung injury induced by traumatic hemorrhagic shock

Exp Ther Med. 2020 Nov;20(5):2. doi: 10.3892/etm.2020.9130. (IF 1.785)

154. Jingyu Song, Taotao Sun, Zhe Tang, Yajun Ruan, Kang Liu, Ke Rao, Ruzhu Lan, Shaogang Wang, Tao Wang, Jihong Liu

Exosomes derived from smooth muscle cells ameliorate diabetes-induced erectile dysfunction by inhibiting fibrosis and modulating the NO/cGMP pathway

J Cell Mol Med. 2020 Nov;24(22):13289-13302. doi: 10.1111/jcmm.15946. (IF 4.486)

155. Xiaomin Su, Qianjing Zhang, Jianmei Yue, Yachen Wang, Yuan Zhang, Rongcun Yang

TRIM59 suppresses NO production by promoting the binding of PIAS1 and STAT1 in macrophages

Int Immunopharmacol. 2020 Dec;89(Pt A):107030. doi: 10.1016/j.intimp.2020.107030. (IF 3.943)

156. Huifang Wang, Li Zhang, Qinpei Li, Shichen Xu, Rongrong Lu

Surface-layer protein produced by Lactobacillus crispatus JCM 2009 ameliorates lipopolysaccharide-induced inflammation through autophagy cross-talk with the NF-κB signaling pathway

Int J Biol Macromol. 2021 Jan 1;166:633-640. doi: 10.1016/j.ijbiomac.2020.10.221. (IF 5.162)

157. Jingya Wang, Lin Yao, Xiaoli Wu, Qi Guo, Shengxuan Sun, Jie Li, Guoqi Shi, Ruth B Caldwell, R William Caldwell, Yongjun Chen

Protection against Doxorubicin-Induced Cardiotoxicity through Modulating iNOS/ARG 2 Balance by Electroacupuncture at PC6

Oxid Med Cell Longev. 2021 Mar 20;2021:6628957. doi: 10.1155/2021/6628957. (IF 5.076)

158. Xiyang Yang, Xingbing Li, Minghao Luo, Yongzheng Guo, Chang Li, Dingyi Lv, Zhe Cheng, Longxiang Huang, Fei-Fei Shang, Bi Huang, Jian Shen, Suxin Luo, Jianghong Yan

Tubeimoside I promotes angiogenesis via activation of eNOS-VEGF signaling pathway

J Ethnopharmacol. 2021 Mar 1;267:113642. doi: 10.1016/j.jep.2020.113642. (IF 3.69)

159. Zhengqing Yu, Yujia Lu, Zhaoyi Liu, Muhammad Tahir Aleem, Junlong Liu, Jianxun Luo, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui Li

Recombinant Toxoplasma gondii Ribosomal Protein P2 Modulates the Functions of Murine Macrophages In Vitro and Provides Immunity against Acute Toxoplasmosis In Vivo

Vaccines (Basel). 2021 Apr 7;9(4):357. doi: 10.3390/vaccines9040357.

160. Wenhua Lei, Junli Li, Changming Li, Li Chen, Fangyang Huang, Dan Xiao, Jialiang Zhang, Jiahao Zhao, Guoyong Li, Tianyi Qu, Hao Zhou, Yanbiao Liao, Mao Chen

MARCH5 restores endothelial cell function against ischaemic/hypoxia injury via Akt/eNOS pathway

J Cell Mol Med. 2021 Apr;25(7):3182-3193. doi: 10.1111/jcmm.16386. (IF 4.486)

161. Huimin Lai, Zhengbiao Yang, Zhaohuan Lou, Feng Li, Feng Xie, Wei Pan, Cong Xu, Lili Zhang, Sheng Zhang, Lijiang Zhang, Mincong Huang

Root Extract of Lindera aggregata (Sims) Kosterm. Modulates the Th17/Treg Balance to Attenuate DSS-Induced Colitis in Mice by IL-6/STAT3 Signaling Pathway

Front Pharmacol. 2021 May 13;12:615506. doi: 10.3389/fphar.2021.615506. (IF 4.225)

162. Wenxiang Mi, Shichong Qiao, Xiaomeng Zhang, Dongle Wu, Linyi Zhou, Hongchang Lai

PRMT5 inhibition modulates murine dendritic cells activation by inhibiting the metabolism switch: a new therapeutic target in periodontitis

Ann Transl Med. 2021 May;9(9):755. doi: 10.21037/atm-20-7362. (IF 3.297)

163. Li-Ting Chen, Ting-Ting Xu, Ya-Qing Qiu, Nuo-Ya Liu, Xin-Yu Ke, Lu Fang, Jie-Ping Yan, Dan-Yan Zhu

Homocysteine induced a calcium-mediated disruption of mitochondrial function and dynamics in endothelial cells

J Biochem Mol Toxicol. 2021 May;35(5):e22737. doi: 10.1002/jbt.22737.

164. Jia-Cen Sun, Xing Tan, Lian-Jie Ge, Ming-Juan Xu, Wei-Zhong Wang

The Release of Nitric Oxide Is Involved in the β-Arrestin1-Induced Antihypertensive Effect in the Rostral Ventrolateral Medulla

Front Physiol. 2021 Jun 18;12:694135. doi: 10.3389/fphys.2021.694135. (IF 3.367)

165. Prince Last Mudenda Zilundu, Xiaoying Xu, Zaara Liaquat, Yaqiong Wang, Ke Zhong, Rao Fu, Lihua Zhou

Long-Term Suppression of c-Jun and nNOS Preserves Ultrastructural Features of Lower Motor Neurons and Forelimb Function after Brachial Plexus Roots Avulsion

Cells. 2021 Jun 28;10(7):1614. doi: 10.3390/cells10071614. (IF 4.366)

166. Weiqing Jiang, Chen Liu, Mingzhu Deng, Fei Wang, Xiao Ren, Yilin Fan, Jiulin Du, Yonggang Wang

H2S promotes developmental brain angiogenesis via the NOS/NO pathway in zebrafish

Stroke Vasc Neurol. 2021 Jun;6(2):244-251. doi: 10.1136/svn-2020-000584.

167. Miaoxuan Sun, Yi Sheng, Yanyan Zhu

Ginkgolide B alleviates the inflammatory response and attenuates the activation of LPS-induced BV2 cells in vitro and in vivo

Exp Ther Med. 2021 Jun;21(6):586. doi: 10.3892/etm.2021.10018. (IF 1.785)

168. Xiao-Xue Liang, Rui-Yu Wang, Yong-Zheng Guo, Zhe Cheng, Ding-Yi Lv, Ming-Hao Luo, An He, Su-Xin Luo, Yong Xia

Phosphorylation of Akt at Thr308 regulates p-eNOS Ser1177 during physiological conditions

FEBS Open Bio. 2021 Jul;11(7):1953-1964. doi: 10.1002/2211-5463.13194. (IF 2.231)

169. Zhanning Xu, Yujie Wei, Guizhong Wang, Haihui Ye

B-type allatostatin regulates immune response of hemocytes in mud crab Scylla paramamosain

Dev Comp Immunol. 2021 Jul;120:104050. doi: 10.1016/j.dci.2021.104050. (IF 3.192)

170. Changliang Huo, Li Wang, Qiuli Wang, Yanbo Yang, Bo Chen

Hydroxysafflor Yellow A inhibits the viability and migration of vascular smooth muscle cells induced by serum from rats with chronic renal failure via inactivation of the PI3K/Akt signaling pathway

Exp Ther Med. 2021 Aug;22(2):850. doi: 10.3892/etm.2021.10282. (IF 1.785)

171. Hao Li, Wenchao Xu, Xiaming Liu, Tao Wang, Shaogang Wang, Jihong Liu, Hongyang Jiang

JAK2 deficiency improves erectile function in diabetic mice through attenuation of oxidative stress, apoptosis, and fibrosis

Andrology. 2021 Sep;9(5):1662-1671. doi: 10.1111/andr.13061. (IF 2.86)

172. Zhen-Jie Wang, Shao-Meng Yu, Jiang-Mei Gao, Peng Zhang, Geoff Hide, Masahiro Yamamoto, De-Hua Lai, Zhao-Rong Lun

High resistance to Toxoplasma gondii infection in inducible nitric oxide synthase knockout rats

iScience. 2021 Oct 15;24(11):103280. doi: 10.1016/j.isci.2021.103280.

173. HongYu Li, LanLan Yang, Ying Jin, ChunXiang Jin

Roles of Endothelial Motilin Receptor and Its Signal Transduction Pathway in Motilin-Induced Left Gastric Artery Relaxation in Dogs

Front Physiol. 2021 Oct 28;12:770430. doi: 10.3389/fphys.2021.770430. (IF 3.367)

174. Qihong Zhang, Tingting Xie, Guodong Mo, Zihao Zhang, Ling Lin, Xiquan Zhang

ACSL1 Inhibits ALV-J Replication by IFN-Ⅰ Signaling and PI3K/Akt Pathway

Front Immunol. 2021 Oct 29;12:774323. doi: 10.3389/fimmu.2021.774323. (IF 5.085)

175. Hui-Hui Zhou, Ye-Ming Zhang, Sheng-Peng Zhang, Qi-Xiang Xu, Ya-Qing Tian, Ping Li, Di Cao, Yong-Qiu Zheng

Suppression of PTRF Alleviates Post-Infectious Irritable Bowel Syndrome via Downregulation of the TLR4 Pathway in Rats

Front Pharmacol. 2021 Oct 7;12:724410. doi: 10.3389/fphar.2021.724410. (IF 4.225)

176. Sen Yang, Xueni Zheng, Meng Qian, He Wang, Fei Wang, Yongzhen Wei, Adam C Midgley, Ju He, Hongyan Tian, Qiang Zhao

Nitrate-Functionalized poly(ε-Caprolactone) Small-Diameter Vascular Grafts Enhance Vascular Regeneration via Sustained Release of Nitric Oxide

Front Bioeng Biotechnol. 2021 Nov 30;9:770121. doi: 10.3389/fbioe.2021.770121.

177. Yanwen Zhang, Yu Yao, Songyang Liu, Yufeng Chen, Shaohong Zhou, Kemin Wang, Xiaohai Yang, Jianbo Liu

Coacervate microdroplet protocell-mediated gene transfection for nitric oxide production and induction of cell apoptosis

J Mater Chem B. 2021 Dec 8;9(47):9784-9793. doi: 10.1039/d1tb01930a. (IF 5.344)

178. Yunxin Zhang, Jianlong Liu, Wei Jia, Xuan Tian, Peng Jiang, Zhiyuan Cheng, Jinyong Li

AGEs/RAGE blockade downregulates Endothenin-1 (ET-1), mitigating Human Umbilical Vein Endothelial Cells (HUVEC) injury in deep vein thrombosis (DVT)

Bioengineered. 2021 Dec;12(1):1360-1368. doi: 10.1080/21655979.2021.1917980. (IF 2.205)

179. Lixian Huang, Bo Zhao, Qunxian Li, Jing Wu, Hui Jiang, Qingbin Li

Ephedrine alleviates middle cerebral artery occlusion-induced neurological deficits and hippocampal neuronal damage in rats by activating PI3K/AKT signaling pathway

Bioengineered. 2021 Dec;12(1):4136-4149. doi: 10.1080/21655979.2021.1953218. (IF 2.205)

180. Yunxing Fu, Zhen Yang, Hongjuan Zhang, Yu Liu, Baocheng Hao, Ruofeng Shang

14-O-[(4,6-Diamino-pyrimidine-2-yl) thioacetyl] mutilin inhibits α-hemolysin and protects Raw264.7 cells from injury induced by methicillin-resistant S. aureus

Microb Pathog. 2021 Dec;161(Pt A):105229. doi: 10.1016/j.micpath.2021.105229.

181. Jingli Zhang, Lixia Liu

Anagliptin alleviates lipopolysaccharide-induced inflammation, apoptosis and endothelial dysfunction of lung microvascular endothelial cells

Exp Ther Med. 2021 Dec;22(6):1472. doi: 10.3892/etm.2021.10907. (IF 1.785)

182. Tao Liu, Guowei Li, Xidong Wu, Shaohua Chen, Siyi Zhang, Hong Han, Hongbin Zhang, Xiaoning Luo, Xiang Cai, Dong Ma

Β-Cyclodextrin-graft-poly(amidoamine) dendrons as the nitric oxide deliver system for the chronic rhinosinusitis therapy

Drug Deliv. 2021 Dec;28(1):306-318. doi: 10.1080/10717544.2021.1876183. (IF 4.902)

183. Lei-Lei Ma, Fei-Juan Kong, Yuan-Ji Ma, Jun-Jie Guo, Shi-Jun Wang, Zheng Dong, Ai-Jun Sun, Yun-Zeng Zou, Jun-Bo Ge

Hypertrophic preconditioning attenuates post-myocardial infarction injury through deacetylation of isocitrate dehydrogenase 2

Acta Pharmacol Sin. 2021 Dec;42(12):2004-2015. doi: 10.1038/s41401-021-00699-0. (IF 5.064)

184. Qian Nie, Miaomiao Liu, Zhimei Zhang, Xuemei Zhang, Chao Wang, Guangyao Song

The effects of hyperuricemia on endothelial cells are mediated via GLUT9 and the JAK2/STAT3 pathway

Mol Biol Rep. 2021 Dec;48(12):8023-8032. doi: 10.1007/s11033-021-06840-w. (IF 1.402)

185. Qing Gao, Tao Yang, Xin-Xin Li, Jun-Wei Xiong, Wei Ma, Yan-Min Xu, Yong Liu, Hong-Yan Zhang, Qi-Yu Wang, Hong-Xuan Wang, Ying Peng, Xiao-Feng Zhu, Yan-Zhong Guan

Nitric Oxide Signaling Pathway in Ventral Tegmental Area is Involved in Regulation of 7,8-Dihydroxyflavone on Alcohol Consumption in Rats

Mol Neurobiol. 2022 Jan;59(1):35-46. doi: 10.1007/s12035-021-02575-8. (IF 4.5)

186. Jingjing Wu, Dongmei Zhang, Linlin Hu, Xiaowei Zheng, Caihong Chen

Paeoniflorin alleviates NG-nitro-L-arginine methyl ester (L-NAME)-induced gestational hypertension and upregulates silent information regulator 2 related enzyme 1 (SIRT1) to reduce H2O2-induced endoth

Bioengineered. 2022 Feb;13(2):2248-2258. doi: 10.1080/21655979.2021.2024325. (IF 2.205)

187. Guoping Mao, Dedong Xin, Qian Wang, Dongmei Lai

Sodium molybdate inhibits the growth of ovarian cancer cells via inducing both ferroptosis and apoptosis

Free Radic Biol Med. 2022 Mar:182:79-92. doi: 10.1016/j.freeradbiomed.2022.02.023.

188. Kai Zhang, Xia Xu, Lihong Hu

Sevoflurane attenuates hepatic ischemia reperfusion injury by the miR-122/Nrf2 pathway

Ann Transl Med. 2022 Mar;10(6):350. doi: 10.21037/atm-22-115. (IF 3.297)

189. Yang Zhu, Jingya Wang, Lin Yao, Yunxuan Huang, Haitao Yang, Xiaojiang Yu, Xinghua Chen, Yongjun Chen

Electroacupuncture at BL15 attenuates chronic fatigue syndrome by downregulating iNOS/NO signaling in C57BL/6 mice

Anat Rec (Hoboken). 2022 May 24. doi: 10.1002/ar.24953.

190. Xiancui Zhang, Huihui Feng, Jintao He, Xili Liang, Nan Zhang, Yongqi Shao, Fan Zhang, Xingmeng Lu

The gut commensal bacterium Enterococcus faecalis LX10 contributes to defending against Nosema bombycis infection in Bombyx mori

Pest Manag Sci. 2022 Jun;78(6):2215-2227. doi: 10.1002/ps.6846. (IF 3.75)

191. Yun He, Hongyu Su, Na Li, Yingying Zhang, Pengjie Zhang, Yumeng Zhang, Yang Ye, Yueming Zhang, Jiaqi Tang, Zhice Xu

In utero hypoxia attenuated acetylcholine-mediated vasodilatation via CHRM3/p-NOS3 in fetal sheep MCA: role of ROS/ERK1/2

Hypertens Res. 2022 Jul;45(7):1168-1182. doi: 10.1038/s41440-022-00935-y. (IF 2.941)

192. Wei Mu, Na Hu, Lan-Hui Zhang, Wei Jiang, Tao Yan, Tian Zhang, An Liu, Yong-Qiang Zhang, Jun Zhao, Lei Shi, Lin-Na Liu

Lonicerae japonicae flos ameliorates radiotherapy-induced mesenteric artery endothelial dysfunction through GTPCH1/BH4/eNOS pathway

Phytomedicine. 2022 Jul 20:102:154146. doi: 10.1016/j.phymed.2022.154146. (IF 4.268)

193. Jiaxin Wang, Jingyu Song, Guoda Song, Yuhong Feng, Jiancheng Pan, Xiaoqing Yang, Zhongcheng Xin, Peng Hu, Taotao Sun, Kang Liu, Wenchao Xu, Tao Wang, Shaogang Wang, Jihong Liu, Yajun Ruan

Acetyl-L-carnitine improves erectile function in bilateral cavernous nerve injury rats via promoting cavernous nerve regeneration

Andrology. 2022 Jul;10(5):984-996. doi: 10.1111/andr.13187. (IF 2.86)

194. Zhihui Fu, Xiaohui Wang, Xuan Lu, Ying Yang, Lingling Zhao, Lin Zhou, Kaikai Wang, Hanlin Fu

Mannose-decorated ginsenoside Rb1 albumin nanoparticles for targeted anti-inflammatory therapy

Front Bioeng Biotechnol. 2022 Aug 15:10:962380. doi: 10.3389/fbioe.2022.962380.

195. Xiaohan Xu, Zhiqiang Tian, Anqi Xing, Zichen Wu, Xuyan Li, Lingcong Dai, Yiyang Yang, Juan Yin, Yuhua Wang

Nitric Oxide Participates in Aluminum-Stress-Induced Pollen Tube Growth Inhibition in Tea ( Camelliasinensis) by Regulating CsALMTs

Plants (Basel). 2022 Aug 29;11(17):2233. doi: 10.3390/plants11172233.

196. Huan Feng, Qi Liu, Zhiyao Deng, Hao Li, Huajie Zhang, Jingyu Song, Xiaming Liu, Jihong Liu, Bo Wen, Tao Wang

Human umbilical cord mesenchymal stem cells ameliorate erectile dysfunction in rats with diabetes mellitus through the attenuation of ferroptosis

Stem Cell Res Ther. 2022 Sep 5;13(1):450. doi: 10.1186/s13287-022-03147-w. (IF 5.116)

197. Liang-Liang Tang, Xu Yang, Shu-Qi Yu, Qi Qin, Rong Xue, Yu Sun, Han Xiao, An-Qi Shang, Jia-Qun Liu, Song-Qi Han, Chen Liang, Jie Lou, Qiu-Shi Wang, Chang-Jiang Yu, Ming-Ming Wu, Zhi-Ren Zhang

Aldosterone-stimulated endothelial epithelial sodium channel (EnNaC) plays a role in cold exposure-induced hypertension in rats

Front Pharmacol. 2022 Oct 6:13:970812. doi: 10.3389/fphar.2022.970812. (IF 4.225)

198. Lu Feng, Zhengmeng Yang, Yucong Li, Nan Hou, Boguang Yang, Xuan Lu, Shanshan Bai, Ming Wang, Xiaoting Zhang, Haixing Wang, Yaofeng Wang, Micky D Tortorella, Gang Li

Malat1 attenuated the rescuing effects of docosahexaenoic acid on osteoarthritis treatment via repressing its chondroprotective and chondrogenesis activities

Biomed Pharmacother. 2022 Oct:154:113608. doi: 10.1016/j.biopha.2022.113608. (IF 4.545)

199. Sheng-Qing Gao, Jia-Jun Shi, Xue-Wang, Shu-Hao Miao, Tao Li, Chao-Chao Gao, Yan-Ling Han, Jia-Yin Qiu, Yun-Song Zhuang, Meng-Liang Zhou

Endothelial NOX4 aggravates eNOS uncoupling by decreasing dihydrofolate reductase after subarachnoid hemorrhage

Free Radic Biol Med. 2022 Nov 20;193(Pt 2):499-510. doi: 10.1016/j.freeradbiomed.2022.10.318.

200. Jian Li, Fan Jia, Zhebin Chen, Jun Lin, Qingbo Lv, Yue Huang, Qiao Jin, Youxiang Wang, Guosheng Fu, Jian Ji

Targeted delivery of liver X receptor agonist to inhibit neointimal hyperplasia by differentially regulating cell behaviors

Biomater Sci. 2022 Nov 8;10(22):6354-6364. doi: 10.1039/d2bm01041k.

201. Xing Tan, Peng Ye, Wan-Yang Li, Yuan Gao, Yue-Qi Leng, Wei Duan, Yang-Kai Wang, Wei-Zhong Wang

The interleukin-enhanced binding factor 3-mediated inhibition of nitric oxide production via phosphoinositide 3-kinase/protein kinase B pathway contributes to central cardiovascular regulation in the

Am J Physiol Regul Integr Comp Physiol. 2022 Dec 1;323(6):R861-R874. doi: 10.1152/ajpregu.00019.2022.

202. Bingliang Lian, Jingwen Gu, Chen Zhang, Zhicong Zou, Meng Yu, Fanghong Li, Xiaoli Wu, Allan Zijian Zhao

Protective effects of isofraxidin against scopolamine-induced cognitive and memory impairments in mice involve modulation of the BDNF-CREB-ERK signaling pathway

Metab Brain Dis. 2022 Dec;37(8):2751-2762. doi: 10.1007/s11011-022-00980-z. (IF 2.726)

203. Ping Xu, Xiaobo Xu, Hanna Fotina, Tetiana Fotina

Anti-inflammatory effects of chlorogenic acid from Taraxacum officinale on LTA-stimulated bovine mammary epithelial cells via the TLR2/NF-κB pathway

PLoS One. 2023 Mar 22;18(3):e0282343. doi: 10.1371/journal.pone.0282343. (IF 2.74)

浏览此产品的顾客也同时浏览：

用户名：
密码：
校验码：
	后续自动登录

	找回密码注册

新冠相关产品

试剂

核酸相关

多肽与蛋白

细胞相关

信号转导

抗体

抑制剂激活剂等

常用试剂

耗材

仪器

技术服务