产品编号 | 产品名称 | 产品包装 | 产品价格 |
P9087-5mg | Semaglutide Intermediate P29 (司美格鲁肽中间体P29) | 5mg | 189.00元 |
P9087-25mg | Semaglutide Intermediate P29 (司美格鲁肽中间体P29) | 25mg | 448.00元 |
P9087-100mg | Semaglutide Intermediate P29 (司美格鲁肽中间体P29) | 100mg | 886.00元 |
CAS Number | Chemical Formula | Molecular Weight | Purity | Grade |
1169630-82-3 | C142H216N38O45 | ~3175.5 | ≥97.0% | Reagent grade |
基本信息(General Information):
Name (Chinese) | 司美格鲁肽中间体P29 |
Name (English) | Semaglutide Intermediate P29 |
Specifications | Reagent grade |
Chemical Formula | C142H216N38O45 |
Synonym (Chinese) | 索马鲁肽中间体;司美格鲁肽中间体;索马鲁肽主链,司美格鲁肽主链;索马鲁肽杂质23;索马鲁肽杂质20;索马鲁肽-29肽主链;索马鲁肽中间体P29;司美格鲁肽29肽前体;司美格鲁肤29肤主链;索马鲁肽中间体29肽 |
Synonym (English) | Semaglutide Main Chain P29; Semaglutide Precursor P29; Semaglutide, intermediate IP-29; Semaglutide Main Chain (9-37); Semaglutide propeptide |
Sequence (Three-Letter Code) |
Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-Gly |
Sequence (One-Letter Code) |
EGTFTSDVSSYLEGQAAKEFIAWLVRGRG |
Source | E. coli |
Reconstitution | Semaglutide Intermediate P29 has very little solubility in water, so it is recommended to suspend it in water first, and add weak alkali dropwise to adjust the pH to 7~9 under stirring (Sodium carbonate is recommended), or refer to the relevant literatures. |
产品描述(Description):
Application | Semaglutide Intermediate P29 is a peptide starting material in the synthesis of Semaglutide. Semaglutide Intermediate P29 shares 97% sequence homology with human GLP-1(9-37). |
General description | Semaglutide Intermediate P29 is an important raw material for the synthesis of GLP-1 receptor agonists such as semaglutide. These drugs have significant effects in the treatment of type 2 diabetes and obesity. Simeglutide can selectively bind and activate GLP-1 receptors, stimulate insulin secretion, inhibit glucose production, and increase GLP-1 levels, effectively controlling blood glucose levels and promoting weight loss [1-2]. |
性质(Properties):
Form | Powder |
Source | Animal origin-free |
安全信息(Safety Information):
Hazard Pictogram Codes | - |
Signal Word | - |
Hazard Statements | - |
Precautionary Statements | - |
Personal Protective Equipment | - |
Hazard Codes (Europe) | - |
Risk Codes (Europe) | - |
Safety Codes (Europe) | - |
RIDADR | - |
WGK Germany | - |
RTECS | - |
Flash Point (F) | - |
Flash Point (C) | - |
产品编号 | 产品名称 | 包装 |
P9087-5mg | Semaglutide Intermediate P29 | 5mg |
P9087-25mg | Semaglutide Intermediate P29 | 25mg |
P9087-100mg | Semaglutide Intermediate P29 | 100mg |
- | 说明书 | 1份 |
-20ºC避光保存,一年有效。
注意事项:本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。
参考文献:1.Dhillon S. Semaglutide: First Global Approval. Drugs. 2018. 78(2):275-284.
2.Marso SP, Bain SC, Consoli A, Eliaschewitz FG, et al. N Engl J Med. 2016. 375(19):1834-1844.
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